Pubdate: Thu, 30 Nov 2000 Source: Half Moon Bay Review (CA) Copyright: 2000, Wick Communications, Inc. Contact: http://www.hmbreview.com/ Author: Deirdre Holbrook Bookmark: http://www.mapinc.org/mmj.htm (Cannabis - Medicinal) DEA APPROVES COUNTY MEDICAL MARIJUANA STUDY San Mateo County announced last Wednesday that the U.S. Department of Justice and Drug Enforcement Administration had approved the first "real world" medical marijuana study at its hospitals and clinics. The yearlong study, scheduled to begin early next year, will test the hypothesis that marijuana reduces pain and nausea and increases the appetites of those suffering from HIV, cancer and other conditions. Because of the federal and state approvals, the study is not expected to be impacted by an expected Supreme Court decision on whether marijuana can be prescribed for medical treatment, as currently permitted in California, despite a federal law prohibiting its use and distribution. The court is hearing arguments on the issue this week. The idea for the San Mateo County study began in 1997, according to San Mateo County Supervisor Mike Nevin, a year after California voters passed Proposition 215, the medical marijuana initiative. The law exempts patients who possess or cultivate marijuana and also physicians who recommend the use of marijuana for medical treatment. Although he doesn't believe in the legalization of marijuana for recreational use, Nevin said that the experience of a friend who was dying from cancer and undergoing chemotherapy got him interested in its value as a medical treatment. But Nevin said this and other anecdotal medical marijuana stories weren't enough to confirm the effectiveness of the drug as medicine. That's why he and other board members lent their unanimous support, as well as funds, to the county administered study, which is the first study in the nation to use AIDS patients in a public clinic setting. "I'm very proud of the county. I think we are a very progressive county," Nevin said. "We are out there directly dealing with the lives of the people, and in this case it's the lives of those people who are suffering. "If we didn't make this available," Nevin added, "it would be a crime." The idea behind the pilot study designed by Dr. Dennis Israelski, chief of infectious disease and AIDS medicine and chief research officer at San Mateo County Hospitals and Clinics, is to set up the framework for future scientific studies that can test the medical basis of the anecdotal stories. "As a physical scientific type, I need evidence and anecdotes don't count as evidence," he said. Although somewhat skeptical about medical benefits of marijuana, he said after hearing testimony from the AIDS patients he has worked with for the past decade, he is excited about the possibilities opened up by the DEA approval. "We were able to push the envelope," Israelski said. In the county study, 60 AIDS patients who have had experience with marijuana will be given controlled doses of the drug, grown at the University of Mississippi, for six weeks. The study will be monitored by patient reports, home visits and medication logs, and requires patients to return prescribed medical marijuana cigarette butts at each clinic visit. However, the study will not try to prove the effectiveness of the drug, according to Israelski. To do this, he would need a much larger group to gather statistically sound evidence of its effects on patients. Instead, the study will focus on the feasibility of successful self-administered, smoked medical marijuana programs. While the scope of the pilot program is limited, Israelski said he hopes the study will set the ground for studies that ultimately may lead to the change in federal classification of the drug, which is now classified as having no known medical benefits. This would make it possible for doctors to legally prescribe marijuana under federal law. He also hopes that the study could lift some stigma around medical marijuana that to date has prevented many private companies from taking the lead in medical marijuana research. "This study is really about people and taking care of people better," Israelski said. "It's about compassion."