Pubdate: Mon, 09 Jun 2000 Source: Chronicle of Higher Education, The (US) Copyright: 2000 by The Chronicle of Higher Education Contact: http://chronicle.com/ Author: Julie L. Nicklin THE LATEST TREND: MIXING PRESCRIPTION DRUGS WITH OTHER SUBSTANCES Coming soon to a campus near you: Ritalin mixed with alcohol or heroin. If the mixing of prescription drugs with alcohol or illegal drugs isn't already occurring on your campus, the odds are good that before long it will be, according to some college health officials and high-school drug counselors. Such concoctions have already caused the deaths of at least two college students in the last few years. As prescription drugs like Ritalin, a stimulant typically used to treat attention-deficit disorder, and Valium, often used for anxiety, become more prevalent, more and more high-school students seem to be getting high by mixing them with each other, with alcohol, or with narcotics. Health officials and counselors acknowledge that they have no hard facts to back up their observations, but they point out that what happens in the high schools usually finds its way to the colleges. "Kids are more and more likely these days to combine substances in a careless way and to not pay much attention to the risks," says Thomas W. Clark, an associate with Health and Addictions Research, a nonprofit research organization in Boston. Jennifer Kairis, a sophomore at Rollins College, in Winter Park, Fla., died in March 1998 after taking a lethal mixture of Inderal, a heart medication sometimes prescribed to control migraines, and two different antidepressants before a fraternity party. According to city police, Ms. Kairis had prescriptions for the two antidepressants, but not for Inderal. The coroner's report showed that her blood contained more than twice the toxic amount of Inderal. Police who investigated the death say that the combination that killed Ms. Kairis was unusual. Students are more likely to combine Valium or Ritalin with other drugs. One such concoction killed Joshua H. Duroff, a senior at Trinity College, in Hartford, Conn., in March. He died after sniffing a mixture of Valium and Xanax, which also relieves anxiety, as well as anti-migraine medication and sleeping pills. According to news reports, none of the medications had been prescribed to Mr. Duroff. He also had been drinking alcohol and using heroin. The roommates, one of whom was hospitalized for three days before regaining consciousness, were arrested on felony drug-possession charges. They have been expelled from Trinity. After Mr. Duroff's death, some students charged that Trinity has long had a drug problem. An editorial in The Trincoll Journal, an online weekly magazine produced by Trinity students, pointed out that four months earlier, an editorial in the student newspaper read: "We have an environment on campus that is incredibly conducive to drug addiction. Drugs are available and seem to be acceptable." Mary D. Thomas, Trinity's dean of students, says that drug use is difficult to track, since students typically are not forthcoming about it, and that mixing prescription drugs had not come to light on the campus before the incident. But since then, she has received "anecdotal reports" of such experimentation by other students at Trinity. Ms. Thomas says she doesn't know to what extent the activity is a problem, but believes that what the four students were doing is not common. "The students were abusing drugs in a way that most students wouldn't contemplate," she says. Officials on other campuses agree. "That is so rare," says Nancy Schulte, coordinator for drug-education services at George Mason University in Virginia. "It was just a bunch of students who were sitting around, saying, 'Hey, we're bored. Let's try this.'" Health officials at the University of Wisconsin at Madison, however, say the abuse of prescription drugs, especially Ritalin, has become disturbingly common. Ritalin is registered as a controlled substance by the U.S. Drug Enforcement Administration, and possessing or distributing the medication without a doctor's prescription is a felony. The drug is finding its way into more and more of America's medicine cabinets as doctors increasingly diagnose youngsters and teens with attention-deficit disorder. According to the D.E.A., the number of prescriptions for such drugs as Ritalin and Dexedrine has increased about 60 percent over the past five years. From January 1990 to May 1995, Ritalin ranked in the top-10 controlled substances most frequently reported stolen from those authorized to have them. When prescribed, Ritalin tablets typically cost 25 to 50 cents each, but they fetch $3 to $15 each on the black market, according to the Indiana Prevention Resource Center at Indiana University. Some who misuse the drug don't take it in pill form. Instead, they crush and inhale the drug, or dissolve it in water and inject it. Many students opt to get high on prescription drugs because they seem more innocent than illicit drugs. "It's a minor-league experience compared to cocaine," says Eric Heiligenstein, the Madison campus's clinical director of psychiatry. "For some students, it's a way to protect your resume while still getting stoned." At Wisconsin last year, some students with Ritalin prescriptions told health-center officials that classmates were either stealing the drug from them, or trying to buy it. So the center began its own informal survey of students who visited the center. Dr. Heiligenstein acknowledges that the survey was more anecdotal than scientific, but says it revealed a "substantial" problem. About 150 Madison students go through the center to get Ritalin prescriptions, he says, and probably an equal number obtain them through other doctors. He estimates, based on interviews with students at the center and conversations with colleagues from around the country, that more than 20 per cent of the Madison campus's students have misused Ritalin or a similar drug on at least one occasion. The levels of abuse, he says, have ranged from taking someone else's medication to stay alert while studying, to mixing Ritalin with alcohol in order to "party longer." The center has since become more selective in prescribing stimulants such as Ritalin and Dexedrine. For example, health officials no longer increase a student's dosages upon request; a doctor must sign off on the change. And a student is allowed only one replacement prescription for one that's been reported lost. Some of the rules were in effect before, but were not strictly enforced, Dr. Heiligenstein says. But toughening up the university's policies, he acknowledges, isn't going to control prescriptions being written and filled off the campus. Though there's little hard data with which to gauge how big a problem mixing drugs has become in high schools, a continuing drug study indicates an increase among teenagers in the illicit use of amphetamines -- psychotherapeutic stimulants that cannot legally be bought or sold without a doctor's prescription. According to the University of Michigan's 1999 "Monitoring the Future" study, the use of amphetamines made a comeback in the 1990's, and usage among 12th graders peaked in 1997, and has remained at the same level for three years. Mr. Clark, of Health and Addictions Research, says that in the past, drug-users would choose a particular narcotic and remain loyal to it. Now, he notes, they're using whatever substances they can get their hands on. "People tend to be less picky these days," he says, "and more willing to try new combinations." - --- MAP posted-by: greg