Pubdate: Tue, 30 Jan 2001 Source: Press, The (New Zealand) Copyright: 2001 The Christchurch Press Company Ltd. Contact: Private Bag 4722, Christchurch, New Zealand Fax: +64-3-364-8238 Website: http://www.press.co.nz/ Author: Yvonne Martin HEALTH MINISTRY BLOCKS USE OF ONE4B The Ministry of Health has stopped the distribution of a legal party substance that doctors and police want banned. The potentially lethal One4b has put comatosed users into hospital. Director-General of Health Karen Poutasi issued a warning yesterday for people not to take products like One4b that contain 1,4 butanediol, an industrial solvent. The United States Federal Drug Administration has warned that 1,4 butanediol can cause dangerously low respiratory rates, unconsciousness, vomiting, seizures, and death. Risks are increased when the chemical is mixed with alcohol or drugs such as depressants. The ministry is working closely with police, who were frustrated yesterday at the rate at which new variants of party drugs were popping up. Police, and the doctors who treated two Auckland nightclubbers taken to hospital unconscious at the weekend, wanted One4b banned before it caused deaths. Detective Senior Sergeant Colin McMurtrie, head of Auckland's drug squad, said One4b had appeared on the streets since the ministry restricted its chemical cousin, Fantasy or GHB. "It's a sad fact of life that every time we legislate against one thing, they are going to find something else," he said. "Chemistry being what it is you can find a variation of anything. That's a problem we're always going to have. We'll continue to chase our tail on these things and play catch-up - hopefully not because someone has died." One4b is marketed as a dietary supplement, but has close ties to GHB (gamma-hydroxybutyrate), the drug made prescription-only following overdoses last January. The 1,4 butanediol it contains turns to GHB in the body. A study in the New England Journal of Medicine this month said 1,4 butanediol had similar health risks to GHB, including potentially fatal toxic effects, addiction, and withdrawal. One4b is made in a Timaru factory, but no adverse effects have been reported by Christchurch users. Outerspace, the distribution company run by Mark and Kate Barlow, said it was safe and beneficial, if taken correctly. The Barlows shun any responsibility for people overdosing on their product. "People do stupid things," said Mrs Barlow. "I believe it is people taking it unwisely. Our responsibility comes in educating people." Dr Keith Bedford, forensic programme manager of Auckland's Institute of Environmental Science and Research, said claiming One4b to be a nutritional supplement placed it outside legislation covering medicines. "It seems to me that they are walking a bit of a tight-rope on that," he said. Dr Bedford said the listing of GHB was so specific under the Medicines Act, and other regulations, that he believed it did not legally cover related substances like One4b and GBL (gamma butyrolactone). MAP posted by: Doc-Hawk