Pubdate: Sat, 03 Nov 2001 Source: New Scientist (UK) Copyright: New Scientist, RBI Limited 2001 Contact: http://www.newscientist.com/ Details: http://www.mapinc.org/media/294 Bookmark: http://www.mapinc.org/pot.htm (Cannabis) SANITY AT LAST Whatever The Dangers Of Cannabis, Draconian Laws Make No Sense IS CANNABIS more - or less - harmful than its legalised cousins alcohol and nicotine? Last week, bang on cue, this hoary old question surfaced yet again as the British government signalled its intent to relax the laws on cannabis possession, and join what is becoming an almost global trend. Other countries have already taken steps towards decriminalising possession, but nobody expected the same from Britain (see p 12). The admission that cannabis is not as harmful as heroin and cocaine goes against everything it's been saying for years. It also leaves the US, which is sticking to this hardline position, increasingly isolated. But not quite alone. One of the strongest attacks on Britain's U-turn came from the nation's bestknown neuroscientist, Susan Greenfield-Oxford pharmacologist, TV presenter and now a member of the House of Lords. In a thundering broadside in a daily paper, Greenfield blasted liberal campaigners who seek to play down the evidence that cannabis permanently damages the brain. It's good to see scientists of Greenfield's standing voicing strong opinions on public issues. However, having reported on the science of cannabis for many years, we have to disagree with her conclusions. To take just one example, she points out that some 7000 milligrams of alcohol are needed to achieve intoxication, whereas for cannabis the figure is just 0.3 milligrams: cannabis is far more potent and hence far more dangerous, she reasons. But what this really means is that you have to have 20,000 times as much alcohol coursing through your veins before you feel the effects. By then your liver is having to work overtime. Alcohol certainly lacks cannabis's ability to act on brain receptors in a potent and specific manner: that is one reason why booze can be so deadly. A number of cannabis users do develop a serious dependency problem. And in excess the drug can lead to poor concentration, even bouts of paranoia. But permanent brain damage? A few lab studies have, it's true, reported that cannabis-like substances can harm nerve cells cultured in the test tube. But such cultures are notoriously fragile, and other studies have found no signs of brain damage in animals given doses far higher than those needed to produce intoxication in humans. And even if they hadn't, it wouldn't matter - at least not as far as changing the laws on cannabis go. The evidence from other countries is that more relaxed laws do not lead to more youngsters using the drug. Wherever cannabis lies in the league table of harmful substances, there seems little point in imprisoning people for possessing small amounts unless this is likely to make the drug less popular. And all the signs are that it doesn't. - --- MAP posted-by: Josh