Pubdate: Fri, 21 Dec 2001 Source: Reason Magazine (US) Issue: Jan 2002, Vol 33, Issue 8, Start page 26 Website: http://www.reason.com/ Address: 3415 S. Sepulveda Blvd., Suite 400, Los Angeles, CA 90034-6064 Contact: 2001 The Reason Foundation Author: Jacob Sullum Note: Reason Senior Editor Jacob Sullum is writing a book about the morality of drug use. SEX, DRUGS & TECHNO MUSIC Last spring, the Chicago City Council decided "to crack down on wild rave parties that lure youngsters into environments loaded with dangerous club drugs, underage drinking and sometimes predatory sexual behavior," as the Chicago Tribune put it. The newspaper described raves as "one-night-only parties-often held in warehouses or secret locations where people pay to dance, do drugs, play loud music, and engage in random sex acts" Taking a dim view of such goings-on, the city council passed an ordinance threatening to jail building owners or managers who allowed raves to be held on their property. Mayor Richard Daley took the occasion to "lash out at the people who produce the huge rogue dance parties where Ecstasy and other designer drugs are widely used." In Daley's view, rave promoters were deliberately seducing the innocent. "They are after all of our children," he warned. "Parents should be outraged by this." The reaction against raves reflects familiar anxieties about what the kids are up to, especially when it comes to sex. As the chemical symbol of raves, MDMA-a.k.a. Ecstasy-has come to represent sexual abandon and, partly through association with other "club drugs," sexual assault. These are not the only fears raised by MDMA. The drug, whose full name is methylenedioxymethamphetamine, has also been accused of causing brain damage and of leading people astray with ersatz feelings of empathy and euphoria (concerns discussed later in this article). But the sexual angle is interesting because it has little to do with the drug's actual properties, a situation for which there is considerable precedent in the history of reputed aphrodisiacs. A relative of both amphetamine and mescaline, MDMA is often described as a stimulant with psychedelic qualities. But its effects are primarily emotional, without the perceptual changes caused by LSD. Although MDMA was first synthesized by the German drug company Merck in 1912, it did not gain a following until the 1970s, when the psychonautical chemist Alexander Shulgin, a Dow researcher turned independent consultant, tried some at the suggestion of a graduate student he was helping a friend supervise. "It was not a psychedelic in the visual or interpretive sense," he later wrote, "but the lightness and warmth of the psychedelic was present and quite remarkable." MDMA created a "window," he decided. "It enabled me to see out, and to see my own insides, without distortions or reservations." After observing some striking examples of people who claimed to have overcome serious personal problems (including a severe stutter and oppressive guilt) with the help of MDMA, Shulgin introduced the drug to a psychologist he knew who had already used psychedelics as an aid to therapy. "Adam," the pseudonym that Shulgin gave him (also a nickname for the drug), was on the verge of retiring, but was so impressed by MDMA's effects that he decided to continue working. He shared his techniques with other psychologists and psychiatrists, and under his influence thousands of people reportedly used the drug to enhance communication and self-insight. "It seemed to dissolve fear for a few hours" says a psychiatrist who tried MDMA in the early '8os. "I thought it would have been very useful for working with people with trauma disorders." Shulgin concedes that there was "a hint of snake-oil" in MDMA's reputed versatility, but he himself considered it "an incredible tool." He quotes one psychiatrist as saying, "MDMA is penicillin for the soul, and you don't give up penicillin, once you've seen what it can do." Shulgin did not see MDMA exclusively as a psychotherapeutic tool. He also referred to it as "my low-calorie martini," a way of loosening up and relating more easily to others at social gatherings. This aspect of the drug came to the fore in the '8os, when MDMA became popular among nightclubbers in Texas, where it was marketed as a party drug under the name Ecstasy. The open recreational use of Ecstasy at clubs in Dallas and Austin brought down the wrath of the Drug Enforcement Administration, which decided to put MDMA in the same legal category as heroin. Researchers who emphasized the drug's psychotherapeutic potential opposed the ban. "We had no idea psychiatrists were using it," a DEA pharmacologist told Newsweek in 1985. Nor did they care: Despite an administrative law judge's recommendation that doctors be allowed to prescribe the drug, the ban on MDMA took effect the following year. Thus MDMA followed the same pattern as LSD, moving from discreet psychotherapeutic use to the sort of conspicuous consumption that was bound to provoke a government reaction. Like LSD, it became illegal because too many people started to enjoy it.Although the DEA probably would have sought to ban any newly popular intoxicant, the name change certainly didn't help. In Ecstasy: The MA Story, Bruce Eisner quotes a distributor who claimed to have originated the name Ecstasy. He said he picked it "because it would sell better than calling it 'Empathy! 'Empathy' would be more appropriate, but how many people know what it means?" In its traditional sense, ecstasy has a spiritual connotation,but in common usage it simply means intense pleasure-often the kind associated with sex. As David Smith, director of the Haight-Ashbury Free Clinic, observed, the name "suggested that it made sex better." Some marketers have been more explicit: A 1999 article in the Yournal of Toxicology (headlined "SEX on the Streets of Cincinnati") reported an analysis of "unknown tablets imprinted with 'SEX'" that turned out to contain MDMA. Hyperbolic comments by some users have reinforced Ecstasy's sexual connotations. "One enthusiast described the feeling as a six-hour orgasm!" exclaimed the author of a 2 000 op-ed piece in Malaysia's New Straits Times, picking up a phrase quoted in Time a couple of months before. A column in The Toronto Sun, meanwhile, stated matter-offactly that MDMA "can even make you feel like a six-hour orgasm." If simply taking MDMA makes you feel that way, readers might reasonably conclude, MDMA-enhanced sex must be indescribably good. Another reason MDMA came to be associated with sex is its reputation as a "hug drug" that breaks down emotional barriers and brings out feelings of affection. The warmth and candor of people who've taken MDMA may be interpreted as flirtatiousness. More generally, MDMA is said to remove fear, which is one reason psychotherapists have found it so useful. The same effect could also be described as a loss of inhibitions, often a precursor to sexual liaisons. Finally, users report enhanced pleasure from physical sensations, especially the sense of touch.They often trade hugs, caresses, and back rubs. Yet the consensus among users seems to be that MDMA'S effects are more sensual than sexual. According to a therapist quoted by Jerome Beck and Marsha Rosenbaum in their book Pursuit of Ecstasy, "MDMA and sex do not go very well together. For most people, MDMA turns off the ability to function as a lover, to put it indelicately. It's called the love drug because it opens up the dancing. But they also talk about a sense of connectedness, especially at raves.Jasmine Menendez, a public relations director in her early 20S who has used MDMA both at raves and with small groups of friends, says it provides "a great body high. I lose all sense of inhibition and my full potential is released....It allows me to get closer to people and to myself." Too Much Fun Euphoria is a commonly reported effect of mDmA, which raises the usual concerns about the lure of artificial pleasure. "It was an incredible feeling of being tremendously happy where I was and being content in a basic way," Stevenson recalls of the first time he felt MDMA's effects. He used it several more times after that, but it never became a regular habit. Menendez, on the other hand, found mDmA "easy to become addicted to" because "you see the full potential in yourself and others; you feel like you won the lottery." She began chasing that feeling one weekend after another, often taking several pills in one night. "Doing e as much as I did affected my relationship with my mother," she says. "I would come home cracked out from a night of partying and sleep the whole day. She couldn't invite anyone over because I was always sleeping. She said that my party habits were out of control. We fought constantly. I would also go to work high from the party, if I had to work weekends. The comedown was horrible because I wanted to sleep and instead I had to be running around doing errands." Menendez decided to cut back on her MDMA consumption, and recently she has been using it only on special occasions. "I think I've outgrown it finally," she says. "I used e to do some serious soul searching and to come out of my shell, learning all I could about who I really am. I'm grateful that I had the experiences that I did and wouldn't change it for the world. But now, being 23, I'm ready to embrace mental clarity fully. Ecstasy is definitely a constructive tool and if used correctly can benefit the user. It changed my life for the better, and because of what I learned about myself, I'm ready to start a new life without it." Sustained heavy use of MDMA is rare, partly because it's impractical. MDMA works mainly by stimulating the release of the neurotransmitter serotonin. Taking it depletes the brain's supply, which may not return to normal levels for a week or more. Some users report a hangover period of melancholy and woolly-headedness that can last a few days. As frequency of use increases, MD's euphoric and empathetic effects diminish and its unpleasant side effects, including jitteriness and hangovers, intensify. Like LSD, it has a self-limiting quality, which is reflected in patterns of use. In a 2000 survey, 8.2 percent of high school seniors reported trying MDMA in the previous year. Less than half of them (3.6 percent) had used it in the previous month, and virtually none reported "daily" use (defined as use on 20 or more occasions in the previous 30 days). To parents, of course, any use of MDMA is alarming, and the share of seniors who said they'd ever tried the drug nearly doubled between 1996 and 2000, when it reached 11 percent. Parental fears have been stoked by reports of sudden fatalities among MDMA users. Given the millions of doses consumed each year, such cases are remarkably rare: The Drug Abuse Warning Network counted nine MDMA-related deaths in 1998. The most common cause of death is dehydration and overheating. MDMA impairs body temperature regulation and accelerates fluid loss, which can be especially dangerous for people dancing vigorously in crowded, poorly ventilated spaces for hours at a time. The solution to this problem, well known to experienced ravers, is pretty straightforward: avoid clubs and parties where conditions are stifling, take frequent rests, abstain from alcohol (which compounds dehydration), and drink plenty of water. MDMA also interacts dangerously with some prescription drugs (including monoamine oxidase inhibitors, a class of antidepressants), and it raises heart rate and blood pressure, of special concern for people with cardiovascular conditions. Another hazard is a product of the black market created by prohibition: Tablets or capsules sold as Ecstasy may in fact contain other, possibly more dangerous drugs. In tests by private U.S. laboratories, more than one-third of "Ecstasy" pills turned out to be bogus. (The samples were not necessarily representative, and the results may be on the high side, since the drugs were submitted voluntarily for testing, perhaps by buyers who had reason to be suspicious.) Most of the MDMA substitutes, which included caffeine, ephedrine, and aspirin, were relatively harmless, but one of them, the cough suppressant dextromethorphan (DXM), has disturbing psychoactive effects in high doses, impedes the metabolism of MDMA, and blocks perspiration, raising the risk of overheating. Another drug that has been passed off as MDMA is paramethoxyamphetamine (PMA), which is potentially lethal in doses over 50 milligrams, especially when combined with other drugs. In 2000 the DEA reported io deaths tied to PMA. Wary Ecstasy users can buy test kits or have pills analyzed by organizations such as DanceSafe, which sets up booths at raves and nightclubs. Nervous Breakdown Generally speaking, a careful user can avoid the short-term dangers of MDMA. Of more concern is the possibility of long-term brain damage. In animal studies, high or repeated doses of MDMA cause degeneration of serotonin nerve receptors, and some of the changes appear to be permanent.The relevance of these studies to human use of MDMA is unclear because we don't know whether the same changes occur in people or, if they do, at what doses and with what practical consequences. Studies of human users, which often have serious methodological shortcomings, so far have been inconclusive. Still, the possibility of lasting damage to memory should not be lightly dismissed. There's enough reason for concern that MDMA should no longer be treated as casually as "a low-calorie martini." If the fears of neurotoxicity prove to be well founded and a safe dose cannot be estimated with any confidence, a prudent person would need a good reason-probably better than a fun night out-to take the risk. On the other hand, the animal research suggests that it may be possible to avoid neural damage by preventing hyperthermia or by taking certain drugs (for example, Prozac) in conjunction with MDMA. In that case, such precautions would be a requirement of responsible use. However the debate about MDMA's long-term effects turns out, we should be wary of claims that it (or any drug) makes people "engage in random sex acts." Like the idea that certain intoxicants make people lazy, crazy, or violent, it vastly oversimplifies a complex interaction between the drug, the user, and the context. As MDMA's versatility demonstrates, the same drug can be different things to different people. Michael Buchanan, a retired professor in his early Los, has used MDMA several times with one or two other people. "It's just wonderful," he says, "to bring closeness, intimacy-not erotic intimacy at all, but a kind of spiritual intimacy, a loving relationship, an openness to dialogue that nothing else can quite match." When I mention MDMA use at raves, he says, "I don't understand how the kids can use it that way." - --- MAP posted-by: Beth