Pubdate: Sat, 10 Feb 2001 Source: Vancouver Sun (CN BC) Copyright: 2001 The Vancouver Sun Contact: 200 Granville Street, Ste.#1, Vancouver BC V6C 3N3 Fax: (604) 605-2323 Website: http://www.vancouversun.com/ Author: Glen McGregor RESEARCHERS TO GET WEAK GRADE OF MEDICAL POT Low-THC marijuana could force test subjects to inhale more toxic smoke, critics say OTTAWA - The federal government will provide researchers with a weakened grade of medical marijuana that could force test subjects to ingest more toxic smoke to gain any benefit from the drug. Health Canada recently gave out a $5.75 million contract to a Saskatchewan firm to produce marijuana for use in clinical trials. The pot will allow researchers to test the drug's effectiveness in treating the symptoms of serious illnesses like AIDS, cancer and multiple sclerosis. But in tendering the contract, Health Canada specified an allowable concentration of the active ingredient, THC, between five and six per cent --lower than the concentration typically found in the home-grown variety which can be more than five times as potent. "It baffles me why they would go to the trouble of creating marijuana at a lower level than the natural plant," says Steven Bacon, a Hepatitis C sufferer who is one of 140 Canadians to receive a special exemption from the government to smoke cannabis to control symptoms. "You must get out of your sickbed and go smoke sub-standard marijuana in order to get it at all," Mr. Bacon said. The marijuana produced for Health Canada would also be available to those, like Mr. Bacon, who receives a special exemption based on medical need. In return for the free pot, they will be required to provide feedback on the effect of the drugs on their illness. But anyone who gets the government grass will have to smoke much more than home-grown marijuana to get the same medicinal benefit as home-grown, Mr. Bacon says. They will also have to inhale more of the 2,000 chemicals and toxins contained in cannabis smoke. "I would have to smoke more, and my lungs would get filled with more crap," Bacon said. "That's not compassionate access to marijuana that (Health Minister) Allan Rock talks about all the time." According to the U.S. National Institute of Health, the average concentration of THC in a marijuana plant runs about three per cent. But the variety favoured by most medicinal smokers, made from just the buds and flowering tops of female plants, has an average concentration of 7.5 per cent and can be as high as 24 per cent. "It certainly is an inferior product," said Loren Wiberg, whose Alberta-based company ZYX Corp. unsuccessfully bid on the production contract. "The stuff that some of these people are growing for medical purposes can be up to 25 per cent THC," Mr. Wiberg said. "They're saying why would the government want them to smoke four times as much? It supposed to be for health and they have to get all this tar and other stuff at a rate of 4:1." But Roslyn Tremblay, of Health Canada, says it was important to establish a consistent THC concentration for research purposes. The level was based on previous scientific research. "The five to six per cent was decided upon on the basis of most of the literature we could see," she said. The production contract does allow Health Canada to ask for higher or lower THC concentrations after the first year of production. - --- MAP posted-by: Josh Sutcliffe