Pubdate: Tue, 07 Jan 2003 Source: Stanford Daily (CA Edu) Copyright: 2003 The Stanford Daily Contact: http://daily.stanford.org/ Details: http://www.mapinc.org/media/952 Author: Megan Clark JUSTICE DEPT TO TRACK RESEARCHERS Act Restricts Certain Researchers' Use of Select Biological Agents The U.S. Department of Justice intends to conduct background checks on all Stanford researchers with access to certain biological agents classified as "non-exempt select agents" by the Center for Disease Control. According to Ellyn Segal, biosafety manager for Stanford's Department of Environmental Health and Safety, there are fewer than 50 people in a handful of labs at Stanford who are currently using these agents. So far, the CDC and the United States Department of Agriculture have only required research institutions, including Stanford, to register their select agents to each agency and have not yet requested names. "Currently the federal government has not set up the mechanism to do the checks," Segal said. "They state that they are 'in the process of setting it up.' " The Department of Justice checks are mandated by the Public Health Safety and Bioterrorism Preparedness and Response Act of 2002. The act was signed into law in June 2002 to establish measures by which to enforce the USA Patriot Act of October 2001. The Patriot Act designated groups of "restricted persons" who are no longer allowed access to non-exempt select agents, a list which includes the Ebola virus, the smallpox virus and the bacteria anthrax. The background checks are intended to determine whether those with access to non-exempt select agents fall into the category of restricted persons and should therefore be denied access to them under the Patriot Act. Restricted persons may still work on versions of select agents which have been exempted by the CDC, a list which includes certain vaccine strains of viruses as well as toxin amounts less than 50 times the standard lethal dose to a human. Restricted persons include those who are on non-immigrant visas from seven nations that the U.S. has deemed to be "state sponsors of terrorism": Cuba, Iran, Iraq, Libya, North Korea, Sudan and Syria. It also includes those who have been committed to a mental institution, unlawful drug users, and those who have been discharged from the armed services under dishonorable conditions. "It's wrong to only focus on international students in this debate," said Ann Arvin, associate dean of research at Stanford. "The restricted persons part includes people that had a dishonorable discharge from the military, which might simply be because they're gay. And what if you were busted in college for selling dope? These are our restricted persons." Steven Block, professor of biological sciences and applied physics, questioned the ability of the Department of Justice to even check such facts on international students. "They didn't think it through completely for what happens if you're a foreigner," Block said. "Our U.S. databases don't specify whether Canadians have been in a mental institution, for example." On Mar. 15, 2002, Charles Kruger, dean of research and graduate policy, sent letters to over 1,100 Stanford researchers with access to select agents, notifying them of the "restricted persons" section of the Patriot Act and requesting them to self-report. "The letter said that if you had a conflict [with the legislation], the University would take all appropriate steps to get you on another project," said Lauren Schoenthaler, an attorney in Stanford's Office of the General Counsel. But according to Segal, no one working on a non-exempt select agent at Stanford has reported to Dean Kruger that he or she falls into the category of "restricted persons." One of Segal's main concerns is the fact that the CDC is making a unilateral decision about the contents of the select agent list. "They're not communicating," she said. "They're taking input, but there's not a dialogue. In fact, Congress mandated that there be no dialogue." According to a CDC press release, the CDC is currently accepting public comments on new, tighter restrictions on select agents that were issued on Dec. 13, and those comments could result in regulatory changes in the future. Stanford previously submitted its input on Sept. 11, 2002, when Segal and Assoc. Vice Provost Larry Gibbs sent a formal statement to the CDC. "We don't know whether they're going to pay attention to our comments or not," Arvin said. According to Schoenthaler, the Patriot and Bioterrorism Response Acts designated two new major restrictions in addition to limiting access to restricted persons. First, the Patriot Act makes it illegal for anyone to possess a biological agent or toxin that is not "reasonably justified," a condition which includes "bona fide research." Second, the Bioterrorism Response Act requires all research institutions to register the possession of select agents as well as the names of those who have access to them. Previous regulations only required institutions to register the transfer of select agents. The Patriot Act carries a fine and up to 10 years in jail while the Bioterrorism Response Act carries a fine and up to five years in prison. FBI has threatened a researcher with Patriot prosecution already This July, Tomas Foral, a graduate student at the University of Connecticut, became the first person charged under the USA Patriot Act for possession of a biological agent with no "reasonably justified" purpose, the first major restriction identified by Schoenthaler. In October 2001, a freezer broke in Tomas Foral's lab, prompting him and a fellow researcher to clean it out and transfer the vials inside to a different freezer. The two reportedly found five to seven vials containing frozen tissue samples from a cow that died of anthrax in 1968. According to the university, Foral was told to destroy the samples. However, he kept two vials in his own freezer, "thinking they may be needed for future research." In response to an anonymous tip by someone who saw the samples in Foral's freezer space, the FBI entered the lab in full biohazard suits on November 27, 2001 and confiscated the two tubes. The FBI subsequently brought charges against Foral in July of this year. Foral, who is a second lieutenant in the ROTC, chose a pretrial diversion program to avoid prosecution. The program will involve two years of community service. "I have no choice," Foral said. "It would be very expensive to go to trial. It would be unaffordable to me." Under current law, it is legal for Foral to possess anthrax as long as he is not a restricted person, and he is using it for "bona fide research." Block said that this case exemplifies the problems with the acts' wording. "Is it sufficient just to possess a select agent in a strain collection, or do I have to be conducting an experiment on it?" he said. "Do I need to have a grant to work on it? "They're going after someone who clearly doesn't fall under the heading of bioterrorist." Arvin has similar concerns about the effectiveness of the acts. "It's like checking the grandmas at the airport," she said. - --- MAP posted-by: Richard Lake