Pubdate: Fri, 7 Nov 2003 Source: Daily Telegraph (UK) Copyright: 2003 Telegraph Group Limited Contact: http://www.telegraph.co.uk/ Details: http://www.mapinc.org/media/114 Author: Celia Hall, Medical Editor Bookmark: http://www.mapinc.org/topics/multiple+sclerosis MS TRIAL OF CANNABIS RESULTS IN CONFUSION Cannabis helped to relieve symptoms in many patients with multiple sclerosis, but doctors say today they could find no physical proof of improvement. The first large scale trial of an active part of cannabis for people with MS has produced a mixed result. Doctors' objective measurements showed no reduction in limb stiffness, but more than half the patients said this had improved. Overall, more patients taking the active drug, tetrahydrocannabinol (THC), reported that spasticity or limb stiffness, pain, spasms and sleep had improved compared with those taking a dummy drug. The trial, published in The Lancet, was funded by the Medical Research Council. It involved 630 people with MS who were given THC or a placebo for 15 weeks. In another part of the study 576 of the patients answered a detailed questionnaire. Many sufferers have found that cannabis provides relief from MS symptoms and have broken the law in using cannabis, a class B drug. It is due to be downgraded to class C. - --- MAP posted-by: Richard Lake