Pubdate: Wed, 26 May 2004 Source: Press, The (New Zealand) Copyright: 2004 The Christchurch Press Company Ltd. Contact: http://www.press.co.nz/ Details: http://www.mapinc.org/media/349 Author: Kamala Hayman Cited: Drug Policy Forum Trust http://www.drugpolicy.org.nz/ WHERE THERE'S SMOKE ... Cannabis makes you mellow, laid-back, carefree. That is the message from the thousands of users in New Zealand as well as lobby groups calling for the decriminalisation of the drug. But evidence from long-term studies around the world shows a clear link between heavy and prolonged marijuana use and psychoses - serious mental disorders in which people lose touch with reality - such as schizophrenia and manic depression. Public attention is focusing on the role of cannabis following the horrific slaying of Dunedin meat worker Kelvin Mercer's six-month-old baby boy and estranged wife. The night before the murderous attack, which also saw Mercer slash the throats of his two older daughters, the 32-year-old had sought help at Dunedin Hospital for his heavy cannabis addiction. Mercer, who set himself alight after the attack, died in hospital before anyone could ask him why he did what he did. Police say it will be weeks before test results will be able to tell them to what extent, if at all, Mercer was under the influence of cannabis at the time of last Thursday morning's attack. But the question of whether cannabis played a role in turning the once caring father into a murderer is an important one for a country where the pro-cannabis lobby has an increasingly strong voice. The warnings from health professionals over the health effects of the drug are mounting. In 1997, aged 42, David Taylor snapped. Drunk and stoned, he bashed Maria Copley to death in Wellington's Basin Reserve. Taylor had grown up in a dysfunctional family of seven children before being thrown onto the streets by his violent father at the age of 14. He spent three months living under bushes in a nearby reserve before it sank in that he was on his own. "So I got into everything - drugs, alcohol, crime ... it was survival. For years I could always hear the old man telling me to go ...'You're not my son, you're not part of this family any more'." Describing himself as "an outcast, a loner", Taylor said he used cannabis as an anti-depressant. "It slows things up, lets you forget for a while." Wellington clinical psychologist Mariette Hopman said at the time that one of the worst things Taylor could have done was smoke cannabis. "Smoking cannabis during adolescence is unbelievably dangerous. The adolescent psyche is not equipped to handle it. "There are times when I feel frantic about this and try desperately to explain to parents that they must get this through to their kids." She said if a young person, especially a teenager on the loose with problems, started to smoke cannabis regularly, the long-term repercussions could be disastrous. "It is the proverbial time bomb, the lethal cocktail." It has been known for 150 years that very heavy consumption of cannabis can cause hallucinations and delusions, Professor Robin Murray, of the London Institute of Psychiatry, told the Guardian newspaper in Britain last year. "This was thought to be very rare and transient until the 1980s, when as cannabis consumption rose across Europe and the US, it became apparent that people with chronic psychotic illnesses were more likely to be regular daily consumers of cannabis than the general population." The hallucinations and delusions of schizophrenia result from an excess of the brain chemical dopamine. Cannabis, like amphetamine and cocaine, increases the release of dopamine in the brain. Murray said starting early clearly increased the risk from cannabis. "If you're taking cannabis daily by age 18, then you are about seven times more likely to develop schizophrenia than the rest of the population." New Zealand should be gravely worried. Our adolescents appear more likely to be smoking cannabis than those in other western nations, says Professor David Fergusson, executive director of the Christchurch Medical School's Health and Development Study. This study followed 1265 children born in 1977 and found more than three-quarters had used cannabis at least once by the time they were 25. This compared with rates closer to 50 or 60 per cent in the United States. Fergusson's researchers also studied the incidence of psychotic symptoms - as opposed to full-blown psychosis - such as hearing things that are not there and delusional beliefs. After taking into account pre-existing levels of symptoms, Fergusson said those who were heavy cannabis users reported two times the rate of pyschotic symptoms. His New Zealand study chimes with international evidence: A Swedish study followed 50,000 Swedish conscripts for 15 years from the age of 18. Those who had tried cannabis by 18 were 2.4 times as likely to be diagnosed with schizophrenia than those who had never used it. The risk increased the more cannabis was used. Australian scientists reported in the British Medical Journal that girls who smoked cannabis were five times more likely to suffer from depression. Their findings were based on a study of 1600 teenagers over seven years. A British Medical Journal editorial in 2002 concluded that the link between cannabis and psychosis was "well established". "The explanation most accepted is that cannabis triggers the onset or relapse of schizophrenia in predisposed people and also exacerbates the symptoms generally ... Length of exposure to use of cannabis predicted the severity of the psychosis, which likewise was not explained by use of other drugs." The evidence in relation to depression is growing. A 15-year follow-up of an adult community sample of 1920 participants in the United States showed that the use of cannabis increased the risk of major depression fourfold. Some have argued that people already suffering psychotic symptoms turn to cannabis to find relief from their distress, that the illness causes the cannabis addiction rather than the other way round. But Fergusson said the "chicken and egg" argument was becoming less plausible. "Studies all around the world suggest that heavy, serious use of cannabis may in fact introduce pyschotic behaviours. The nature of that link is still not known, but it does look as though heavy use may disorder brain chemistry." Of course, the case should not be overstated. Alcohol abuse can also cause psychosis and psychosis occurs in only a minority of people. As Fergusson points out, doubling a small risk still means only a small minority of the population are likely to be susceptible. If cannabis consumption increases - and this week the Drug Policy Forum Trust meets in Wellington to discuss legalising it for medicinal use - caution must be taken. - --- MAP posted-by: Richard Lake