Pubdate: Thu, 22 Apr 2004 Source: Toronto Sun (CN ON) Copyright: 2004, Canoe Limited Partnership. Contact: http://www.canoe.com/NewsStand/TorontoSun/home.html Details: http://www.mapinc.org/media/457 Author: Jason Botchford Bookmark: http://www.mapinc.org/coke.htm (Cocaine) CORONER CALLS IT THE DEADLIEST DRUG There are few commonly used recreational drugs more dangerous than cocaine, says Ontario's deputy chief coroner. Dr. Jim Cairns said if cocaine is among several drugs detected in the blood of someone who died in a drug-related death it is almost always considered the cause of death. "The toxicity level is just so high," Cairns said. He said it is an alkaloid, a member of the chemical family that includes nicotine, caffeine and morphine. The drug is a central nervous system stimulant derived from coca leaves in South America and is changed into Cocaine Hydrochloride in jungle labs in South America, said Dr. Jamie McCloud, an American professor who has studied the properties of street cocaine. McCloud said the product that leaves South America is about 75% pure and includes kerosene, leaded gasoline and an assortment of other manufacturing byproducts. Before it gets to a Toronto user it is often "cut" or diluted it with talcum powder, cornstarch or amphetamines, local police said. The drug alters the absorption of the neurotransmitters, causing the brain to "believe" it is satiated, McCloud said. Cocaine decreases desire for food, increases blood pressure and alters cardiac rhythm, breathing and body temperature. It causes irregularity in the way the heart functions, heart attacks and an increase in the rate of both respiration and body transpiration. - --- MAP posted-by: Larry Seguin