Pubdate: Mon, 17 May 2004 Source: Vancouver Courier (CN BC) Copyright: 2004 Vancouver Courier Contact: http://www.vancourier.com/ Details: http://www.mapinc.org/media/474 Author: Jennifer Maloney Bookmark: http://www.mapinc.org/find?131 (Heroin Maintenance) THE FIX Greg, a 37-year-old addict, has made five attempts in 10 years to kick the heroin habit: "There's never enough drugs for the people down here. It doesn't matter how much money you have, there's never enough. You always want more." By Dan Toulgoet. Twenty-eight-year-old Marcella stands in the rain on the corner of Jackson and East Cordova streets. In one hand, she clutches a broken umbrella, its body held together with a string. In the other hand hangs a bulky plastic bag. The skin over her full cheekbones is soft, a result of her aboriginal and Polish background. Letting out an exaggerated yawn-she hasn't slept in 24 hours-she agrees to be interviewed. It turns out Marcella, who was born and raised on the East Side, has been injecting cocaine into her brittle veins since she was 18. She lifts the sleeves of her wool coat to reveal countless bumps and bruises on her arms and wrists. "This one's two years old," she says, pointing to a scar on her forearm that has barely faded. The jugular veins in her neck are tender to the point that they bleed when she touches them to demonstrate their sensitivity. "If I go to sleep they'll heal up, but if I put a needle in there, they'll collapse." Marcella, who doesn't want her last name used to protect her 10-year-old son, is shooting up almost every hour of the day. Although cocaine is her drug of choice, she uses heroin to keep herself warm during the winter months and to mellow out her cocaine highs. For Marcella to successfully support her drug habit, she needs to sell her body for $20 to $200 a trick. During her 13 years as a sex-trade worker, Marcella has been beaten and raped five times, but it hasn't been enough to make her stop. Each time, she just wanted to find more drugs-as fast as possible. She's wanted to quit, but that would mean leaving the Downtown Eastside, where all her "friends" and connections are. This winter, she even looked into a detox centre in northern B.C., but there was a three-week wait. Addicts like Marcella don't plan that far in advance-their lives aren't just day-by-day, they're moment-by-moment. To give people like Marcella a chance at a better life, a group of researchers is planning an experimental trial starting this summer that would see a select group of Vancouver addicts given free, prescription heroin. It's part of a national project involving 470 heroin addicts from Toronto, Montreal and Vancouver. (Montreal and Toronto are moving ahead on getting their university-based sites ready, but aren't allowed to begin until Vancouver is ready.) Volunteers would be long-term addicts who live in the Downtown Eastside and who have failed methadone treatment. Half the subjects would be tested with methadone, the others with heroin. Eighty-eight people would get prescription heroin and 70 would get methadone. The national clinical trial, which is funded by Health Canada, is called the North American Opiate Maintenance Initiative or NAOMI, and it's based on successful experiments in European countries like Switzerland, the Netherlands and Germany. Switzerland, particularly, saw stunning results in addicts who participated. According to the 1997 Swiss Heroin Prescription Report, both the number of offenders and number of criminal offences decreased by about 60 per cent during the first six months of prescription heroin treatment, based on information obtained from the patients and from police records. Income from illegal and semi-legal activities also dropped to 10 per cent, down from 59 per cent originally. The number of addicts with permanent employment more than doubled to 32 per cent from 14 per cent, while the number of unemployed fell by more than half, to 20 per cent from 44 per cent. Users given heroin were found to have a better chance at stabilizing their lives than those on methadone or abstinence-based programs. Local researchers had hoped their own program would start a full year ago, but have been stymied by red tape and difficulties finding a location. Now, however, it looks like the trial won't begin until September. It won't come a moment too soon for Greg, a 37-year-old addict who's made five attempts in 10 years to kick the heroin habit. He's now on methadone, a synthetic replacement for heroin. Methadone, an opiate-blocker, levels his heroin cravings and prevents his body from getting ill. In early January, he decided he'd had enough of waking up nauseous and bleaching out needles in a desperate attempt to fix. Unfortunately, he's on such a low dose-methadone is also addictive and doctors don't want to overprescribe it-that he admits he can still feel the effects of heroin and shoots up periodically. In the last week of February, he had to have oxygen pumped into him after he collapsed at the safe injection site on East Hastings. Greg wonders why getting the prescription heroin trial off the ground has taken so long. He's not alone. Rumours of free heroin have been spiraling around Vancouver's Downtown Eastside for months. Every day, volunteers at VANDU are asked about it. "Everyone wants to know what they can do to get on it," Greg says. Greg grew up in Burnaby, where he started snorting cocaine at parties on weekends with a tough crew of teenagers almost 20 years ago. It wasn't until he became reliant on a syringe to take the edge off his cocaine high that he moved to the place where a short-term fix outweighs a long dreary reality. "[The Downtown Eastside] is the last stop. When you're at the bottom, something's going to change. You're either going to die, to jail, or you're going to pull through." In 1986, Greg started a marijuana grow-op with some friends he'd met while working as a parking attendant during Expo. The profit from their grow-op enabled them to buy $1,300-ounces of cocaine every three days. It was in this grow house on 62nd and Fraser Street that Greg first shot up heroin. "I was lying down on the bed and I had no worries and I was warm -it was so great," Greg remembers. "I hate to say it, but that feeling that people are first looking for when they do heroin-your whole body is warm and you have no pain at all-that doesn't last forever. You start getting junk sick in the morning or six to eight hours after because your body is addicted." Just as his body changed, so did his financial luck. Greg's grow house was busted. The $30,000 profit he'd saved was spent buying ounces of coke and heroin and "partying with people." The money only lasted four months and then he had to find other ways to support his habit. "We were doing break and enters, mostly breaking into clothing stores and stealing cars around the city," he says. At that time, computers were new on the market and Greg and a small crew of addicts would smash into offices and steal computers, pawning them to dealers in exchange for drugs. At his peak, Greg was spending $400 a day on cocaine and a couple hundred on heroin. "One person creates a lot of crime," he says now. "There are only a small percentage of people doing the greatest percentage of crime in Vancouver. "When I see kids first down here, I can see what's coming because I've seen so many times how it starts. They come down here and they think they're partying and stuff. They get together with the dealers and they're having a good time making money and stuff. And then things change very quickly because the drugs are so God-damned expensive. There's never enough drugs for the people down here. It doesn't matter how much money you have, there's never enough. You always want more." A solid yellow line separates the emergency patient traffic down the narrow hallway at St. Paul's Hospital. Two adjacent stalls accommodate a men's and women's washroom near the Comox Street entrance. In bright green marker, the words "I love heroin" are printed neatly over the faded beige paint in the men's stall. "Every minute of their time is spent trying to get drugs," says the national coordinator of the NAOMI trial, Kathy Sayers, sitting in her small office six floors up. Sayers, who got involved in the project through her work with UBC's Centre for Health Evaluation and Outcome Sciences at St. Paul's Hospital, is impressed by the success of countries like Switzerland in reducing crime and improving addicts' lives with free prescription heroin. But she's learned the hard way that legally dispensing a hard drug that law enforcement agencies have spent years trying to crush is an uphill fight. Unlike in Switzerland, it's not the national government that's initiating the prescription heroin experiment here and in the U.S. It's a group of inquisitive clinicians and researchers dependent on government approval to get the experiment going. The U.S. government has continually refused to back the experiment. But Canada's federal government provided $8.1 million for the project from the Canadian Institutes of Health Research in February 2002. Since then, it's been a bumpy road. Aside from dealing with political opposition from people who think researchers would be better off promoting detox and rehabilitation than so-called harm reduction, researchers have had to clear a series of bureaucratic hurdles. Getting clinical trial approval from Health Canada was the first challenge. In her office at St. Paul's Hospital, Sayers points to a large binder on the top shelf of her bookcase, with the initials CTA for clinical trial approval written in black on its spine. "You've got to be very careful when you start asking for human volunteers. There's lots of safeguards for them." First, researchers had to find a formulation of heroin that Health Canada would approve of. The first manufacturer they found was within budget, but the formulation didn't meet Health Canada's standards, which stipulated that the heroin must be pharmaceutical grade and could not be cut with other drugs and the dispensing of the dosage has to be exact-unlike on the street. The NAOMI team then found a European manufacturer that could produce the exact formulation Health Canada would approve of, but the price was higher than they'd budgeted. As the lesser of two evils, the NAOMI team opted to buy the expensive heroin. "Finding a manufacturer was difficult," Sayers says. "Health Canada tells us what formulation they'll allow, so we have to find a manufacturer that could do that exact formulation. As you can imagine, there aren't tons." The whole process took six months. After finally locating a manufacturer in Europe, the NAOMI team was hit with yet another obstacle. The United Nations' International Narcotics Control Body, an arm of the UN Drug Control Program, requires that any manufacturer producing heroin must not have a surplus. This meant the amount of heroin NAOMI imported into Canada had to exactly balance how much the manufacturer made. Almost two years after the proposal was initiated, in January 2002, the project received clinical trial approval from Health Canada-a process that normally takes six to eight weeks. "These are all just regulatory hurdles," Sayers says. "They're not roadblocks. They're mostly to protect the participants to make sure that they're getting good drugs." Ironically, what they're getting on the streets is anything but good drugs. In the last few years, the Downtown Eastside has had an influx of dirty drugs, infused with speed and toxic substances. "That's a really bad turn for here, for speed to get into cocaine," Greg says. "The amphetamines really damage people's brains." Dealers are able to buy cheap chemicals and mix cocaine with impure substances in their bathtubs, before selling it on the street for greater profit. Desperate addicts then shoot the mix into their veins. That's why for many addicts, getting onto heroin maintenance doesn't just mean not having to work the corner or steal or rob people-it means getting pure heroin, instead of these tainted products, says Greg. Because heroin has never been tested as a pain reliever in North America, Health Canada has to grant NAOMI an exemption from the Narcotics Act. That meant the NAOMI team had to first find a site to dispense the heroin in the Downtown Eastside that both the city and Health Canada would approve of. It wasn't easy. In Montreal and Toronto, where the universities are central to the drug problem, it wasn't difficult-the sites were simply based on campus. But because the University of British Columbia is far from the heart of Vancouver's drug problem, the Downtown Eastside is the only location feasible for the experiment. NAOMI first picked a site at 659 E. Hastings St. but withdrew its application to the city last fall after neighbours complained the location was too close to an elementary school and an abstinence-based recovery house. The city also noted it was six or seven blocks outside the core of the Downtown Eastside. Tracking down a replacement wasn't easy, since, aside from the difficulty of finding a willing landlord, the heroin site had to meet stringent physical requirements. It had to be about 3,000 square feet with two separate entrances to accommodate both the methadone and heroin clinics. It also had to be renovated to meet high security standards under a certain budget. After hearing that NAOMI researchers were having trouble locating a site, Phil Bouvier, executive director for Central City Mission Foundation, a charitable organization that offers low-income housing to Downtown Eastside residents, invited the team to look at one of his empty rental spaces. The first space didn't meet NAOMI's requirements, but another site owned by the Mission did. That site is located at 84 West Hastings St., right in the core of the Downtown Eastside. It had two separate entrances and sufficient square footage. It was perfect except for one problem-it wasn't vacant. Vera Ward is no stranger to drug addicts. She's been ministering to them at her Downtown Eastside Revival Centre church at 84 West Hastings St. for 11 years, sometimes as many as 500 a week. At age 76, Ward would likely have continued doing this for the rest of her life. But last January, she and her husband Ron, both recovering alcoholics, learned they were being evicted so Central City Mission could collect market value for the space, to help fund the single-room-accommodation suites upstairs. The proposed tenant was the NAOMI project. The Wards turned down an offer of another site across the street, saying they're too old to move. "I was heartsick," Ward said about the prospect of prescribing free heroin to the drug addicts she works with. "If it was for anything else, if it was going to benefit the community, I'd be glad to give up our church. But they have no idea if it's going to work." Ward, who took over the church after her brother, who had been running it since 1948, passed away, said the move would only hurt addicts desperate to be rid of heroin. "I love chocolate. Put me in a chocolate factory and I'd die. "Here we are trying to get them off the drug and they throw us out to put them back on it." Nonetheless, on March 15, the 84 West Hastings St. site was unanimously approved by the city after 17 delegations spoke in favour of the heroin trial. NAOMI now has full approval for the site, and is awaiting a building permit, expected to come through shortly. Renovations should be complete sometime in summer, at which point NAOMI will seek the Narcotics Act exemption. The trial is expected to begin in September, and last two years. Martin Schechter, a UBC medical researcher who's heading the NAOMI trial in Vancouver, has said testing free heroin on drug users will benefit all Vancouverites. "These 160 or so people, they will not have to engage in criminal activity because they will know that their allotment of heroin is going to be provided by a doctor," Schechter told the Vancouver Sun newspaper last year (it was difficult for the Courier to get people to speak on the NAOMI project because of the political sensitivity of the issue). "The whole idea of the study is that if [drug addicts] don't have to go stand on the street and sell sex or break into cars or burglarize your house, there may be a window of opportunity where you could actually get them to break that cycle and get them out of that spiral." Jim Boothrayd, spokesman for NAOMI, anticipates that critics of harm reduction will be watching the results of the trial particularly closely. "Obviously, this is a highly innovative and controversial study. It's never been tried in North America." There's no chance the project would be expanded by NAOMI, since any major changes must be approved by the funding body, Health Canada, says Boothrayd-"This is a limited, short-term scientific trial"-although if it's successful, the government could choose to establish prescription heroin programs. Back at the street corner, Marcella, who describes herself as a functioning addict, says not having to track down her drug supply would give her a chance at a regular life. "If I were to know I had my dope there, I'd be able to sleep better and concentrate on normal things because I wouldn't have to chase so much." - --- MAP posted-by: Josh