Pubdate: Sun, 04 Jun 2006 Source: Charleston Gazette (WV) Copyright: 2006 Charleston Gazette Contact: http://www.wvgazette.com/ Details: http://www.mapinc.org/media/77 Note: Does not print out of town letters. Author: Scott Finn and Tara Tuckwiller Bookmark: http://www.mapinc.org/find?232 (Chronic Pain) Bookmark: http://www.mapinc.org/heroin.htm (Heroin) Bookmark: http://www.mapinc.org/find?136 (Methadone) Series: The Killer Cure (3 Of 11) WHAT IS METHADONE? What it is: Methadone is a synthetic opiate developed by the Germans during World War II as a substitute for morphine. What it isn't: Methadone often is confused with "meth," or methamphetamine, an illegal stimulant commonly cooked in clandestine labs. Methadone is a completely different -- and legal -- drug. Uses: Until recently, methadone was given mostly to heroin addicts to suppress their cravings. Now, doctors are increasingly prescribing it as a painkiller. Dangers: Methadone acts differently from other painkillers. It can stay in the body for an unusually long time, making it possible for therapeutic doses to build up to a toxic level. Methadone may take a while to make its effects felt. Patients may take an extra dose, thinking the first one isn't working, and an overdose can result. An overdose of methadone may cause a patient to fall into a deep sleep and eventually stop breathing. Methadone is more dangerous when taken with certain other drugs, such as Valium and Xanax. Reactions to methadone vary dramatically. A dose that is therapeutic for one person might kill someone else.