Pubdate: Tue, 01 Aug 2006 Source: Vancouver Sun (CN BC) Copyright: 2006 The Vancouver Sun Contact: http://www.canada.com/vancouver/vancouversun/ Details: http://www.mapinc.org/media/477 Author: Frances Bula Bookmark: http://www.mapinc.org/coke.htm (Cocaine) Bookmark: http://www.mapinc.org/hr.htm (Harm Reduction) Bookmark: http://www.mapinc.org/meth.htm (Methamphetamine) MAYOR SEEKS DRUG MAINTENANCE FOR COCAINE AND METH ADDICTS Experimental Program Would Provide Substitute Drugs To Addicts Vancouver needs an experimental drug program for cocaine and crystal meth addicts that would give them substitute drugs to help them quit or stabilize their habits, says Mayor Sam Sullivan. While a medical experiment is already underway for heroin addicts that provides some local addicts with daily doses of heroin, Sullivan said he's confident it will eventually result in a heroin-maintenance program. "It's just a matter of time. You've just got to work it through the system. Now we've got to move into the next stage." The next stage is what addiction experts say is the newest and most-needed research, "stimulant maintenance" trials, which would provide substitute drugs to cocaine and crystal-meth addicts. Local researchers have frequently made the point that cocaine is much more widely used in Vancouver than heroin, so a program for treating cocaine would be of greater benefit. "I want a stimulant maintenance trial going," said Sullivan. "I've almost assumed [a heroin-maintenance program] is going to happen." Sullivan said his primary focus is improving life for the city's sex-trade workers. He noted that statistics indicate 88 per cent of them are using stimulant drugs. Sullivan has had a stream of advice and opinion on options for Vancouver's drug problem since he told The Vancouver Sun in late April that he wanted to see more heroin provided to city drug users, that he was working with staff on what kind of program the city should support, and that he had received substantial donations to provide money for some kind of program. He received visits from several groups, including researchers at the local Centre for Excellence in HIV-AIDS, who within days of his April statement e-mailed him a "brief draft proposal" marked confidential. While neither Sullivan nor the Centre for Excellence would confirm that the centre has made a proposal, Sullivan said a "very good group" has come forward with a proposal for a stimulant trial. Other international researchers who attended a harm-reduction conference in Vancouver in April advised the mayor that stimulant maintenance trials were more needed than heroin trials. The mayor also has had at least three donors offer money for a drug-maintenance program -- the type is unspecified. Two anonymous donors have committed to $500,000 and $10,000 respectively, and MDS Metro Laboratory Services founder Dr. Donald Rix has committed $50,000. The mayor said he simply wants to act as a broker between potential donors and any agency that wants to run a program, but he wants to ensure something happens sooner rather than later. "It's going to take too long through the government processes. We need to push it forward." Ron Morgan, a peer counsellor at the current supervised-injection site Insite, said he thinks a stimulant-maintenance program would be a great help. "Crack cocaine is the most expensive way to do coke, so that means people here are stealing from each other, fights are breaking out over almost nothing. A stimulant-maintenance program would help people stabilize their lives, stop them craving." User Brian Alleyne also agreed it would be a benefit. If Vancouver started a stimulant-maintenance trial, it would be a first for Canada, but not for North America. Several research groups have been experimenting with replacement drugs for cocaine and crystal meth. One of the longer-term researchers is Dr. John Grabowski, a psychiatry professor at the University of Texas and director of the university's substance-abuse research centre. Grabowski, in an hour-long interview from Houston Monday, said that even in the more conservative American states, interest has been growing in finding substitute drugs for stimulant users. For many years, researchers tried to use anti-depressant-type drugs to deal with cocaine or other stimulant addictions, but had very little success. He started his first trials in 1995 using a different approach. Instead of anti-depressants or other calming-type drugs, he began experimenting with replacement drugs that are also stimulants. He began with Ritalin in 1995, used methamphetamine for some trials before the "war against crystal meth" made it impossible to get, and then moved on to trials with dextroamphetamine. All of those showed signs of effectiveness, mostly with people who are active and heavy cocaine users, as opposed to intermittent or binge users. Effectiveness, in the drug-addiction-research world, means primarily that people in the studies reduce their cocaine use. Other clinical measurements also show they report fewer signs of depression and behavioral disturbances. Grabowski says his studies, unlike some European ones, don't claim to provide evidence that drug substitutions reduce crime. "Whether they continue to engage in criminal activity, we have no way of measuring," said Grabowski. "Here's the problem -- people expect too much of medications. If people walk in the door and their prime way of getting money is to be a thief, treating them is not going to change that." What drug-maintenance programs can do is provide a chance for users to attain some "biological and behavioural stability," he said. That's in part because the drug is supplied, but also because it's provided through a slow-release mechanism that allows users to maintain a plateau, rather than going up and down with the euphoric highs and subsequent crashes that characterize street use. That evenness allows them to possibly get some order in their lives and get more benefit from therapy and behaviour-control counselling. Grabowski, who was contacted by city drug policy coordinator Don MacPherson several months ago about a possible visit to Vancouver, said he is convinced the current wave of stimulant-maintenance trials will produce a drug combination that will prove effective in helping cocaine and crystal-meth users who are trying to quit. The trick then will be finding jurisdictions with the "clinical and political will" to turn those experimental successes into health programs. Other countries that have tried stimulant-maintenance programs include Australia, Britain, the Netherlands, Switzerland, and Finland. E-MAILS TO MAYOR BACK DRUG PROGRAM A Vancouver Sun freedom-of-information request for all e-mails in the nine days after Mayor Sam Sullivan said on April 21 that he was trying to support and find funding for drug maintenance programs indicated 21 of 30 comments were supportive. "Your harm-reduction proposal deserves to be given a chance, even if it is a temporary solution while we search for a long-term resolution," said one, who offered $10,000 to support a Sullivan plan. Another wrote: "I completely support your idea, and frankly, would like to thank you for having the bravery to risk your career on something so important." On the other side, "I am appalled," said another. "I'm not saying that what you have ahead of you is an easy task or there is a good solution but giving drugs to drug addicts is not a good thing." Another said "We CANNOT save everyone -- only those who want to be saved from whatever ails them. . . . By making it 'easy' to get drugs we are doing nothing but enabling people to remain on drugs." And a third: "How dare you take from good hard-working people and let others suck off that with nothing other than a worse habit to show for it." - --- MAP posted-by: Beth Wehrman