Pubdate: Mon, 22 Jan 2007 Source: Bay Of Plenty Times (New Zealand) Copyright: 2007 Bay Of Plenty Times. Contact: http://www.mytown.co.nz/bayofplenty/ Details: http://www.mapinc.org/media/2926 Author: David Dunham PARTY PILLS USERS GAMBLE WITH BRAIN AND BODY HARM If you take a party pill you should brace yourself for a cocktail of dangerous and debilitating side effects that may cause permanent harm. The ingredients in the pills _ eight million of which have been sold since they became legal to sell to over-18s in 2000 _ can cause serious toxicity in your body even at recommended doses, according to the National Poison Centre (NPC). In severe cases, a person may suffer a seizure, movement disorder, cardiac disorder, hyperthermia, liver or kidney toxicity, the Dunedin-based NPC told the Bay of Plenty Times. It also emerged yesterday that a major Government-funded study into the effects of the benzylpiperazine or BZP _ the main ingredient in party pills _ was aborted because of health side effects on its 35 participants. The subsequent report said BZP had severe negative effects, especially if taken with alcohol. Among the symptoms experienced by the mostly-male test group were vomiting, vision problems, dizziness, confusion and agitation. Dehydration, fatigue, convulsions, hallucinations, nausea and feelings of being stressed are all known as common problems directly linked from taking party pills containing piperazine and BZP. The NPC said there were at least 65 different brands of party pills on the market with newer formulations containing up to 10 times the BZP content of older brands. On Saturday, the Bay Times reported that the use of party pills by under-age Bay teenagers was rife and many users were unaware of the serious side effects. The Ministry of Health said people aged under 18 were at particular risk of being harmed by the pills as their brains were not fully developed. But people aged under 18 were not the only ones giving medical experts cause for concern. The Poisons Centre said it had enquiries from breastfeeding or pregnant women who had taken party pills wanting to know about the risk to their infant or foetus. Andrew Brown, a poison information officer with the centre, said pills containing piperazine and BZP may induce severe toxicity in pregnant women which in turn may cause toxicity in the foetus and increase complications in pregnancy. In addition, a withdrawal syndrome may be induced in the child following delivery. There was very little information about the pills or how they interact with other medicines or medical conditions. "We do not know what a safe dose is, what is dangerous and what may be lethal. Additionally, no one has described what kinds of effects they have on the human body," Mr Barnes said. Concern about party pills appears to run the spectrum of local health professionals. Pharmacist Mark Arundel, of Bethlehem Pharmacy, said if BZP caused health problems then it should only be available through prescription or banned altogether. "There is a general awareness that because it is freely available it is safe. It is a very interesting area and it raises a whole lot of issues. You cannot keep control of it if there are not controls around it," Mr Arundel said. Accident & Healthcare on Second Ave, an after hours GP service in Tauranga, has had two cases in the past month of people coming in complaining they were suffering from the side effects of party pills. Manager Dave Gilbert said on both occasions the patients were sent to Tauranga Hospital for treatment. The number of patients turning up at the hospital's emergency department complaining of side effects of party pills is slowly increasing, department head Dr Derek Sage said. People coming in the day after taking them stayed in hospital for anywhere between three and 24 hours with symptoms such as a racing heart, anxiety and paranoia. While the Bay Times has only been given anecdotal details about party pill usage in the Western Bay, one in five of people aged between 13 and 45 who took part in a Massey University study last year said they had tried party pills at least once. David Benton, clinical director of Hanmer Clinic, a drug outpatient treatment centre in Tauranga, said party pills could be considered a dependent drug. "If you take something that makes you feel good and then you do not take it and feel bad you tend to return to taking it," he said. "It probably falls into a category such as alcohol in that it panders to the belief that you cannot have a good time without having something in you." - --- MAP posted-by: Elaine