Pubdate: Sun, 04 Mar 2007 Source: Texarkana Gazette (TX) Copyright: 2007 Texarkana Gazette Contact: http://www.texarkanagazette.com/ Details: http://www.mapinc.org/media/976 Author: Lynn LaRowe, Texarkana Gazette PATH TO DESTRUCTION: METHAMPHETAMINE A DEADLY DRUG Methamphetamine makes permanent holes in precious brain tissue. The metabolites, or byproducts, of the substances cooks use in unsanitary labs kill healthy cells, resulting in permanent damage. When her brother killed himself at the age of 24, Dr. Mary Holley, a gynecologist and founder of MAMa, Mothers against Methamphetamine, took it upon herself to learn about meth. Holley's brother had only begun using the drug two years before. Cold medicines are combined with an acid and a base, such as lye, Drano, battery acid, antifreeze, and kerosene, to create the deadly drug. "You can't break this stuff down into carbon dioxide and water like you do everything else," Holley writes in a widely distributed pamphlet called, "Meth Death." "Your body turns it into ... caustic chemicals and they eat holes in your brain. This brain tissue does not grow back." Meth's addictive and damaging effects begin immediately in the body of a first-time user. "Meth does in one night what it takes a year of alcoholism to do to the brain," Holley said in a speaking engagement Sunday evening at Heritage Baptist Church in Texarkana. "One time, and you will use again. You may think it's your decision, but it's not. Meth is in control from the first second it enters the body." Holley says 75 percent of people who try meth will use again within one week. In a video created by MAMa entitled "The High is a Lie," images of Holley's brother, shortly before his death, illustrate meth's effects. "I can never get back what I lost that night," Holley quoted her brother as saying about the first time he smoked ice, a highly popular form of meth. Meth first creates a daylong high that induces feelings of ecstasy, confidence, intelligence, strength and control in the user, Holley said. For a time, the intensity of the high increases with each use, but this euphoric period does not last. Meth first creates a daylong high that induces feelings of ecstasy, confidence, intelligence, strength and control in the user, Holley said. For a time, the intensity of the high increases with each use, but this euphoric period does not last. Side effects from the drug, including anxiety and muscle spasms, are usually self-medicated with sedatives such as Xanax or Valium, powerful benzodiazepenes with life-threatening and addictive properties of their own, or powerful painkillers such as Oxycontin or Hydrocodone, an opiate commonly known as Vicodin, also addictive. Eventually the prescription drugs don't calm the side effects as more and more meth is used, leading meth addicts to mix their poison with heroin. The high that lured the user into addiction slowly dissipates after repeated use. The addict now uses only to relieve the "crash," a period of paralyzing depression, paranoia, anxiety and often psychosis. Meth is no longer fun but stopping means 12 to 18 months of living hell as nerve cells that once maintained mood and personality slowly heal, Holley said. It was during his crash period Holley's brother found a gun in a relative's home and chose to end his pain. "He didn't know it would stop someday," Holley said. "He blew his brains out because he just couldn't stand it anymore." Holley says this happens because meth turns off important brain functions over time. Cells containing dopamine, a neurotransmitter that is crucial to regulating emotions and rational thinking, are turned on like a faucet, dumping the powerful chemical into the brain for 12 to 20 hours. Cells that usually tell the dopamine-containing ones to turn off cannot communicate with them any longer and eventually shut down. Nerves controlling levels of other important brain chemicals such as seratonin are also affected, Holley said. When the dopamine in these nerve cells is depleted, a crash occurs. At first, the crash lasts only a day or so but its severity increases dramatically over a short time. "Eventually the crash controls your life," Holley said. While using, the excess of neurotransmitters and other damaging effects on brain function lead to visual, sensory and emotional hallucinations, Holley said. "Not only does the person see snakes crawling on the ground, they feel bugs are covering their skin," Holley said. Users commonly pick sores on their skin in an effort to rid themselves of the phantom "meth mites." Emotional hallucinations cause a person to feel baseless rage, often leading to violent, deadly behavior. Holley displayed photographs depicting children of meth-addicted caregivers. One child was nearly bald because her mother's meth-using boyfriend plucked them out one by one while high. Holley warns that the child of the meth user often begins using at an early age with the result being death or incarceration as a juvenile. Recovering from a meth addiction is painful and hard. For 12 to 18 months the brain continues to experience debilatating side effects such as severe depression, psychosis, aggressive behavior, the inability to experience pleasure and memory loss, for example, as the body endures the crash. Gradually the brain begins to heal and some semblence of normalcy returns, Holley says. "But the wiring is different now, and some of the damage is permanent." Meth does not discriminate among races, genders, or socioeconomic status, which Holley demonstrates by displaying a photograph of Florida Gov. Jeb Bush's meth-using daughter. "If it can happen to her it can happen to anyone," Holley said. Before a user reaches rock bottom and makes the decision to get clean or is forced to stop using by the criminal justice system, Holley recommends friends and family show the user "tough love." Providing money, housing and other forms of support simply enable the user to continue sinking deeper into their addiction. During the crash period the addict probably does best in a lock-down residential setting where medical and psychological treatment is available. Relapse rates are high when addicts are free to seek meth, Holley says. "The most horrible agony any family goes through is watching a child disintegrate from meth," Holley said. "The addict is going to break your heart." - --- MAP posted-by: Steve Heath