Pubdate: Fri, 21 Mar 2008 Source: Ancaster News (CN ON) Copyright: 2008 Brabant Newspapers Contact: http://www.ancasternews.com Details: http://www.mapinc.org/media/3386 Author: Richard Leitner Bookmark: http://www.mapinc.org/mjcn.htm (Cannabis - Canada) Bookmark: http://www.mapinc.org/youth.htm (Youth) NOT EVERYONE'S HIGH ON POT'S RISING STATUS Young Brains Can't Handle Today's Powerful Weed, Psychiatrist Warns Cannabis has gone mainstream in a big way since the era of Reefer Madness, the unintentionally funny 1936 B-flick that became a cult hit in the 1970's for its hysterical warnings that smoking pot will lead to manslaughter, murder, rape, suicide or, at best, eternal insanity. Boomer-age politicians generally admit to having at least tried it -- if with questionable candor in the case of former U.S. president Bill Clinton, who claimed he didn't actually inhale -- and marijuana's cultural influences are everywhere, in music, art, film and on prime-time TV, where its starring role in the retro sitcom That 70's Show barely raised an eyebrow. In Canada, it's now legally prescribed for medical uses, including to counter nausea and weight loss from chemotherapy. The federal Liberals under former Prime Minister Jean Chrtien even mused about decriminalization, as politicians have periodically done since the 1972 Le Dain Commission recommended relaxing what is apparently one of the country's most-flouted laws. Though Prime Minister Stephen Harper's Conservative government put a quick damper on any such laissez-faire thoughts, the proverbial genie is way out of the bong: an estimated one in six Canadians between the ages of 15 and 64 smoke marijuana, according to one recent United Nations study. Suzanne Archie makes it clear she's not a pot prude, particularly when it comes to moderate use by adults -- which she defines as once or twice a month. She also acknowledges pot has some benefits at low levels, like lessening anxiety, and "can't say I haven't tried it." But the psychiatrist at St. Joseph's Healthcare is concerned that early use is potentially creating a ticking time bomb for those who are already at risk of developing mental illness. Today's weed is not only way stronger than the stuff her generation smoked in the Sixties and Seventies -- THC, the active ingredient, is now as high as 15 per cent, compared to one to five per cent back then -- but kids are puffing it at a much younger age, she said. Whereas boomers typically began regular use between 19 and 24 -- that is smoking it perhaps once a week -- the age range has dropped to 15 to 20, and sometimes younger. A 2004 Canadian study, for instance, found a quarter of 14-year-olds smoke pot -- a figure Dr. Archie believes is now higher. As with binge drinking, early cannabis use is a particular concern for those vulnerable to her area of expertise -- psychosis, which is "a disturbance in understanding reality," like hearing noises that aren't there or perceiving neutral behaviour as threatening -- because the brain is still developing. "We don't fully understand how much is going on during those teenage years with all those hormonal changes," Dr. Archie told a recent public forum on the relationship between marijuana and psychosis. "There are lots and lots of changes in the brain, and that's when people are actually vulnerable to developing mental illness. It's not really when people are 30, it's actually from puberty to about age 25, when all this brain development is going on," she said. "When you're 15, your brain is making all these circuits all over the place. This is why teenagers are impossible, because their frontal lobes are connecting to the emotional centres in the brain, and you know what the emotions are like in a teenager. "And this is all new growth. We didn't know that 10 years ago. We thought their brains were just smaller versions of adult brains." What doctors also didn't realize until more recently, Dr. Archie said, is that humans are hard wired for pot: the brain has special receptors that are specifically designed to process it. This is because our bodies naturally produce low levels of cannabis, which becomes particularly active for women during childbirth. "We are supposed to experience a certain amount of cannabis and that's why we have cannabis receptors in the brain," Dr. Archie said. "It makes perfect sense because it is an analgesic and it helps you to forget about pain," she said, adding with a laugh. "It's probably helped mankind to continue because women forget. Think about it, you completely forget about how painful childbirth was, because otherwise you wouldn't be having (more) children." While this may or may not help explain why men can never remember to put down the toilet seat, the hardwiring has a darker side in people with a genetic vulnerability to mental illness. Dr. Archie said people with a predisposition toward schizophrenia, for instance, have a higher number of cannabis receptors in their brain, making them more prone to addiction.Pot disrupts their brain's dopamine levels and causes hallucinations, she said. Studies suggest early use is also a problem for teens with a genetic vulnerability to psychosis. She cites a long-term New Zealand study that tracked 1,000 children as they grew up. It found those who smoked pot once or twice per week between the ages of 13 to 15 were nearly four times more likely to experience psychosis, compared to those who did not. Even when a family history was factored out, the pot smokers were still twice as susceptible. But another study found regular pot use played a negligible role in psychosis for younger teens who had no genetic risk. Yet it did show that those at high risk were significantly more likely to report hallucinations in their mid-twenties -- or 10 years after their regular use. "It's really that teenage use that's problematic," said Dr. Archie, who advises those who want to indulge in pot or alcohol to hold off until they're 19. "I think what people need to hear is that it's not safe for adolescents to be using this stuff, that their brains cannot handle it and that toxic levels of this stuff, just weekly use, creates psychiatric problems down the road," she said. "It's kind of like trying to prove cigarette smoking causes cancer back in the Fifties. That's really the level where we're at now." - --- MAP posted-by: Jay Bergstrom