Pubdate: Tue, 17 Jun 2008 Source: Edmonton Journal (CN AB) Copyright: 2008 The Edmonton Journal Contact: http://www.canada.com/edmontonjournal/letters.html Website: http://www.canada.com/edmonton/edmontonjournal/ Details: http://www.mapinc.org/media/134 Author: Pamela Fayerman, Vancouver Sun; Canwest News Service Referenced: The CMAJ article http://drugsense.org/url/5JzL2sVG Bookmark: http://www.mapinc.org/mmj.htm (Marijuana - Medicinal) Bookmark: http://www.mapinc.org/mmjcn.htm (Marijuana - Medicinal - Canada) www MEDICAL MARIJUANA A DOWNER FOR SOME PATIENTS Researchers Find Most Side-Effects Not Serious VANCOUVER - The use of medical marijuana to relieve pain and other disease symptoms can cause a huge range of adverse effects, say researchers with the University of B.C. and McGill University. Researchers analyzed 31 studies from around the world conducted over the past 40 years and found that while nearly 97 per cent of adverse events were not serious or life-threatening, medicinal marijuana users still have an 86-per-cent increase in the rate of non-serious adverse effects, such as drowsiness and dizziness, compared to non-users. The study published in today's Canadian Medical Association Journal found the risk of suffering serious, adverse effects requiring hospitalization is not elevated in medicinal marijuana users, compared to non-users. However, studies on patients taking marijuana have shown that rarely, serious effects have been documented, including multiple sclerosis relapses, convulsions, respiratory and gastrointestinal disorders, urinary infections, cancer tumour progression and psychiatric disorders. Research on recreational marijuana users shows they have an increased risk for psychosis and cancer, but the authors say no one should assume that the same effects would apply to those using it for medicinal purposes, due to different delivery systems and doses. Dr. Jean-Paul Collet, one of the study authors who is a UBC professor and pediatrician leading clinical research at B.C. Children's Hospital, said that because of the small numbers of cases and patients, it is impossible to say whether the serious effects were directly related to the cannabis products. "There is statistical validity to the non-serious effects like nervousness, paranoia, hallucinations, dizziness and anxiety. But it would be incorrect to talk about cannabis medicines causing an excess risk of death at this point. We cannot make any conclusions about any of the serious events. We need more information and more research in order to see whether there are any trends," said Collet, who worked at McGill University when the study was undertaken. - --- MAP posted-by: Richard Lake