Pubdate: Tue, 09 Sep 2008 Source: Canadian Medical Association Journal (Canada) Copyright: 2008 Canadian Medical Association Contact: http://www.cmaj.ca/ Details: http://www.mapinc.org/media/754 Author: Stephen Kish LIMITING PRODUCTION OF CRYSTAL METH [One of the authors responds:] Joseph Caplan's suggestion that the chemicals involved in the synthesis of methamphetamine hydrochloride be regulated is highly relevant to the prevention of crystal meth use, but this issue was outside the scope of my review article.1 Canada's Precursor Control Regulations include requirements, as Caplan recommends, to control precursors and other substances used in the production of methamphetamine, including ephedrine, pseudoephedrine and red phosphorus.2 Before 2003 these regulations did not exist and there was much concern, especially in the United States, about the export of precursors from Canada for illicit methamphetamine production.3 It can be argued that the Canadian legislation should be strengthened by requiring more frequent reporting by the chemical industry of the sale of precursors, by requiring licensing of end-users and by other approaches such as requiring that anhydrous ammonia (a nitrogen fertilizer used in methamphetamine synthesis) be stored in government-approved containers.4 There is also the controversial (at least in Ontario) question whether cold medications containing pseudoephedrine should be sold only in pharmacies (i.e., not in corner grocery stores) and only behind the counter so that the extent of use can be better monitored. Because of a severe problem with methamphetamine abuse, Oklahoma has required that such cold medications be sold only behind pharmacy counters in this state. Curious about the availability of pseudoephedrine in Canada, I contacted a Canadian Internet pharmacy and visited a major Canadian drugstore: the Internet pharmacy would sell customers only 60 tablets of a medication containing pseudophedrine whereas in the drugstore the quantity that customers could purchase was limited only by the availability of the drug. It is obvious that methamphetamine precursors used for legitimate purposes must be tightly controlled. However, it now appears that precursors smuggled from outside of the country are often used to manufacture methamphetamine in Canada.5 Drug prevention using precursor control thus remains a challenge. STEPHEN KISH PhD Human Neurochemical Pathology Laboratory Centre for Addiction and Mental Health Toronto, Ont. - ---------------------------------------- Footnotes Competing interests: None declared. REFERENCES 1. Kish SJ. Pharmacologic mechanisms of crystal meth. CMAJ 2008;178:1679-82. 2. Office of Controlled Substances. Regulatory requirements under the Controlled Drugs and Substances Act (CDSA): precursor control regulations (PCR) international. Ottawa: Health Canada; 2007. Available: www.hc-sc.gc.ca/dhp-mps/substancontrol/chem-chim/international-eng.php (accessed 2008 Aug 7). 3. Office of the Press Secretary. US releases annual narcotics certification report [press release]. Washington: The White House; 2003 Jan 31. Available: www.usis.it/file2003-01/alia/a3013106.htm (accessed 2008 Aug 7). 4. Government of Manitoba. Safeguard your supply of anhydrous ammonia. Winnipeg: Government of Manitoba; 2008. Available: www.gov.mb.ca/agriculture/news/crystalmeth-en.pdf (accessed 2008 Aug 7). 5. National Drug Intelligence Center. National drug threat assessment 2008: methamphetamine. Johnstown (PA): The Center; 2007. Available: www.justice.gov/ndic/pubs25/25921/meth.htm (accessed 2008 Aug 7). - --- MAP posted-by: Steve Heath