Pubdate: Tue, 02 Mar 2010 Source: Ottawa Citizen (CN ON) Copyright: 2010 The Ottawa Citizen Contact: http://www.canada.com/ottawacitizen/letters.html Website: http://www.canada.com/ottawacitizen/ Details: http://www.mapinc.org/media/326 Author: Kate Kelland, Reuters Bookmark: http://www.mapinc.org/pot.htm (Cannabis) CANNABIS USE DOUBLES INCIDENCE OF PSYCHOSIS Young people who smoke cannabis or marijuana for six years or more are twice as likely to have psychotic episodes, hallucinations or delusions than people who have never used the drug, scientists said on Monday. The findings adds weight to previous research which linked psychosis with the drug and will feed the debate about the level of controls over its use. Despite laws against it, up to 190 million people around the world use cannabis, according to United Nations estimates, equating to about four per cent of the adult population. John McGrath of the Queensland Brain Institute in Australia studied more than 3,801 men and women born between 1981 and 1984 and followed them up after 21 years to ask about their cannabis use and assessed them for psychotic episodes. "Compared with those who had never used cannabis, young adults who had six or more years since first use of cannabis were twice as likely to develop a non-affective psychosis," McGrath wrote in a study published in the Archives of General Psychiatry journal. They were also four times as likely to have high scores in clinical tests of delusion. A "dose-response" relationship showed the longer the duration since first cannabis use, the higher the risk of psychosis-related symptoms. McGrath said, however, that "the nature of the relationship between psychosis and cannabis use is by no means simple" and more research was needed to examine the mechanisms at work. - --- MAP posted-by: Jo-D