Pubdate: Wed, 25 Jul 2012 Source: Sacramento Bee (CA) Copyright: 2012 The Sacramento Bee Contact: http://mapinc.org/url/0n4cG7L1 Website: http://www.sacbee.com/ Details: http://www.mapinc.org/media/376 Author: Paul Armentano SCIENCE SUPPORTING MEDICINAL POT IS CLEAR A dozen years ago, California lawmakers did something extraordinary. They authorized investigators throughout California to conduct a series of FDA-approved, gold standard trials to assess whether cannabis is safe and effective as a medicine. In all, researchers conducted more than a dozen clinical studies examining whether cannabis could meet objective standards of safety and therapeutic efficacy. For example, investigators at the University of California, San Francisco, assessed whether vaporizing cannabis could rapidly and consistently deliver the plant's active ingredients to patients in a manner that is far safer than smoking. It could. At UC San Diego, clinicians examined whether inhaling cannabis posed potential harms to the immune system, particularly in subjects suffering from immune-compromised conditions like HIV. It didn't. And at universities throughout the state, investigators studied whether marijuana provided statistically significant relief in a number of hard-to-treat conditions, such as multiple sclerosis and neuropathic (nerve) pain. Cannabis did so consistently. Summarizing the results of California's novel, nearly $9 million medical cannabis research program in the Open Neurology Journal, the program's director, Dr. Igor Grant of UC San Diego wrote: "Based on evidence currently available, the (federal) Schedule I classification (of cannabis) is not tenable; it is not accurate that cannabis has no medical value, or that information on safety is lacking." Nonetheless, policymakers particularly those in Washington have responded to these most recent scientific findings with no more than a collective yawn. Despite pledging to let "science and the scientific process ... inform and guide decisions of my administration," neither President Barack Obama nor Congress have taken any steps to amend federal law or federal policy to reflect the scientific reality that marijuana possesses well-established therapeutic value. In fact, this administration has taken just the opposite approach. In 2011, the Obama administration quashed out-of-hand an administrative petition that sought federal hearings regarding the present classification of cannabis as a substance with "no currently accepted medical use in treatment in the United States." In its rejection, the administration alleged, "The drug's chemistry is not known and reproducible; there are no adequate safety studies; there are no adequate and well-controlled studies proving efficacy; the drug is not accepted by qualified experts; and the scientific evidence is not widely available." Yet, the findings from California's 12-year-old study program show that each of these claims is demonstrably false. Of course, when it comes to marijuana policy in the United States, science has never played a significant role. This reality is unlikely to change any time soon. Speaking to the New York Times in 2010, a spokesman for the National Institute on Drug Abuse one of the primary agencies involved in crafting U.S. drug policy acknowledged: "As the National Institute on Drug Abuse, our focus is primarily on the negative consequences of marijuana use. We generally do not fund research focused on the potential beneficial medical effects of marijuana." Even more alarming, a 2011 White House report affirmed that only 14 researchers in the United States possess the legal permission to even conduct research assessing the effect of inhaled cannabis in human subjects. "Change we can believe in?" Hardly. More like: "See no evil; hear no evil." It is long past time to reject the notion that we as a society possess insufficient evidence regarding the safety and efficacy of cannabis. The truth is that we know plenty. Most of all we know that there remains no valid scientific reason to justify the continued targeting, prosecution and incarceration of those Americans who consume cannabis responsibly. - --- MAP posted-by: Jay Bergstrom