Pubdate: Wed, 09 Jan 2013 Source: Bakersfield Californian, The (CA) Copyright: 2013 The Bakersfield Californian Contact: http://www.bakersfield.com/ Details: http://www.mapinc.org/media/36 Author: Brik McDill Note: Brik McDill, Ph.D., of Tehachapi has spent 40 years in private practice in clinical and forensic psychology. YOUNG BRAINS MAY NOT BE READY FOR SUPER-WEED OF WORLD TODAY Whoa there, sugarfoot, not so fast on the marijuana thing. In the rush to legalize pot we may be overlooking some important (and risky) things about it: that one of its properties is that it's an hallucinogen capable of producing sudden and randomly occurring flashbacks (more on that below); and that it can have scrambling and stunting effects on a developing brain. Some background. Pot now is 1,300 percent more potent than in the 1960s and '70s. Through selective cross-fertilizing enhanced strain with enhanced strain, pot today is turbo-charged. Weed back in the Age of Aquarius was weak to the point where users had a hard time separating out the effect of inhalation hyperventilation from the THC effect of pot itself (THC is the psychoactive substance in the mix of combustion chemicals inhaled). Even then users got wasted and whacked out doing strange and dangerous things. I was stationed at the hospital at the San Francisco Presidio, then later in my military hitch at the Oakland Army Base adjacent to U.C. Berkeley, and I saw my share of spaced-out active and residual pot-brain muddlement. A cherished neuroscience professor of mine made the remark that some people's brains were sturdy things that could, unfazed, withstand many onslaughts of mind-scrambling chemicals; others' brains, however, were barely held together with thumbtacks and spit and disintegrated completely in the face of even minor chemical disturbance. And there was no knowing ahead of time who had which kind of brain until, for the unlucky, it was too late. Don't get me wrong, I'm not the ad-man for the 1930s movie "Reefer Madness." But a word of caution is in order before we swing open the doors to widespread recreational pot use. Marijuana is a hallucinogen, which means it's a thought and sensation scrambling chemical that makes one see, hear, feel, and sense things that aren't real. It can produce pleasant things and things that are scary. It can give one the giggles or it can bring on terror. It can make one feel wholly blissed-out or suddenly paranoid and delusional. Sensations are scrambled away from their typical pathways and sensory projection areas; sounds are seen, colors tasted, visions heard. And there's knowing ahead of time what the coming trip will be. And that was back in the 1970s, smoking today's feeble precursors. Brains are organs of high sensitivity and functional complexity which no one fully scientifically understands even now. Despite powerful brain imaging and mapping technology, and probes and other exploratory instrumentation measuring in the nanos, a lot of brain function is still veiled in mystery. We're just now discovering that the white glial stuff of the brain we thought merely fed and held in place the important grey stuff functions very much like a complex co-existing wrap-around brain of its own. We know that female brains continue to develop into the late teens and very early twenties, while the male brain doesn't complete its development until the mid-, even late-twenties. All the while, during the brain's delicate development, circuits and centers are flaring to life in genetically pre-determined, complex sequences -- each circuit and center dependent on the successful lighting-up of its precursors. We also know that the highest level of drug use occurs during those same years. Do we see a problem here? While the brain is wiring and building itself, do we really want to throw chemicals into it that can knock this delicate process out of whack? Pot is not like alcohol or other legal drugs. Some early researchers placed pot somewhere on the psychoactive continuum somewhere among caffeine, nicotine, and tea. Problem is that scaling is wrong for today's pot-on-steroids; and pot is fat soluble, not water soluble like the others. Water soluble means easily metabolized and washed out of one's system; fat soluble means it hangs around long after it's taken in and continues its effect for a long time. It also means it gets absorbed into and stored in fatty tissue (fat cells) to be later re-released to have its delayed out-of-the-blue effect. This is only partially explored territory. A little caution can go a long way. - --- MAP posted-by: Jay Bergstrom