Pubdate: Wed, 02 Apr 2014 Source: Daily Herald, The (Provo, UT) Section: Science and Society Copyright: 2014 The Daily Herald Contact: http://www.heraldextra.com/component/option,performs/formid,1 Website: http://www.heraldextra.com Details: http://www.mapinc.org/media/1480 Author Duane Jeffery, Community Columnist Note: Duane Jeffery is an emeritus professor of biology at Brigham Young University. AMBITIOUS TRIALS IN LEGALIZING DRUGS Let it be clear at the outset: I am definitely not an advocate for recreational psychoactive drugs! But I've never been enamored with staying uninformed on the issue either. So with that caveat, and with two countries now experimenting a little with legalization of such drugs, let's summarize a bit. It should be well-known that the states of Colorado and Washington have recently legalized certain broad uses of recreational marijuana and are still working out the fine details of how to control the use thereof. Uruguay has thrown the doors wide open for marijuana. And New Zealand has now formalized legislation for all new psychoactive drugs, while still banning the ones that have heretofore been internationally illegal. First consideration: Why such legalization? A primary reason is that the effort to control such drugs has proven incredibly expensive and only marginally effective at best. It is variously estimated that the U.S. has spent over a trillion dollars in this effort and has incarcerated scores (likely hundreds) of thousands of persons for extensive periods at great expense. The efforts to understand the real effects of many of these drugs is complicated by the fact that there is no quality control - researchers have little way of knowing precisely what the users were really using. In the early days of LSD, for instance, researchers bought "LSD," assertedly of considerable purity, from a dozen or more "reputable" street dealers, and found LSD in less than half the samples. Reliable research is thus deeply compromised. And then there is the clamor of those who find such drugs pleasurable, "harmless," and meritorious. So, think some governments, why not neutralize the criminal trade, produce the substances under well-regulated control, ensure quality and credible research, tax the drugs and raise much-needed money - and save the enforcement expense? The four governments above are trying it - - but all recognize that it's not that simple. For starters, users frequently mix drugs - imbibing alcohol along with the drugs being apparently the most common such complication. So "research" is a problematic rationale. Money and decriminalization seem to be the larger issues. The March 8 issue of the magazine New Scientist extensively reviews the New Zealand experiment. New synthetic drugs are constantly coming onto the market (undercover!) and are legal until formally banned. In the late 1990s BZP (benzylpiperazine) showed up. By 2008 sufficient negative reports had accumulated to ban it. Mephedrone quickly followed. That too was shortly banned, but there is no shortage of others to fill the void. European authorities identified 24 new synthetics in 2009, 41 more in 2010, and 73 more in 2012. (New Scientist charts numbers in six different categories.) The trend is pretty clear. So New Zealand still bans current illegals, but will permit new ones that meet certain standards of "demonstrated safety." Such drugs are then cleared to conduct a massive experiment on the population and see what effect this may have on society. Needless to say, other nations are watching this bold/desperate experiment with interest. And in the meantime, there is no guarantee that many other drugs are not also slipping in through the legal coverages. How safe do the accepted drugs have to be? A concept of "low risk" is being pursued: harm to individuals, harm to society, risk of addiction. But compared to what? One proposed standard is "half as harmful as alcohol." Given the above complications, it is easy to see how surveillance is going to be very difficult and may eventually even rival enforcing laws for illegality in terms of cost. Personally, I have always thought I needed every brain cell I had to even minimally compete - why stress them any more than what happens by unavoidable fatigue? Duane Jeffery is an emeritus professor of biology at Brigham Young University. - --- MAP posted-by: Jo-D