Pubdate: Sun, 25 Jan 2015 Source: Waterloo-Cedar Falls Courier, The (IA) Copyright: 2015 The Waterloo-Cedar Falls Courier Contact: http://www.wcfcourier.com/ Details: http://www.mapinc.org/media/3510 Author: Jeff Reinitz CHEMISTRY ARGUED IN SYNTHETIC DRUG SENTENCING CEDAR RAPIDS - In the world of synthetic drugs, sometimes it takes a chemistry lesson to get to the bottom of what's in the Mylar packet. Sometimes it takes rats. On Friday, a federal judge heard about both during the penalty phase for a former Cedar Falls man and his mother, an Evansdale resident, who were convicted of selling potpourri and bath salts that mimicked illegal drugs. Authorities said Mary Ann Ramos, 53, sold Alpha-PVP and XLR-11 as a manager at an I-Wireless store in Cedar Rapids. She was found guilty during a June trial. Her son, Earl "E.J." Ramos, 27, pleaded guilty to similar charges in connection with substances sold at Five Star Stacks in Waterloo. Both were charged following a nation-wide crackdown on synthetics dubbed "Operation Synergy" in 2013. Although they are illegal because of their similarity to other drugs, the new substances aren't yet listed on drug equivalency tables courts apply to federal sentencing guidelines in order to determine punishment. During Friday's hearing in U.S. District Court in Cedar Rapids, Michael Van Linn, a drug science specialist with the U.S. Drug Enforcement Administration in Washington, D.C., said Alpha-PVP bath salts are chemically similar to methcathinone, a stimulant that sits on the DEA's Schedule I, a list of controlled substances that have a high potential for abuse with no medical use in the United States. "They share the same core chemical structure," Van Linn said. Jordan Trecki, a DEA pharmacologist, testified Alpha-PVP had methcathinone-like effects on the human central nervous system. And he said studies with lab rats showed the animals couldn't tell the difference between Alpha-PVP and methamphetamine and between methcathinone and methamphetamine. Defense attorney John Lane, who is representing Earl Ramos, and Michael Lahammer, Mary Ramos's attorney, asked about Alpha-PVP's similarity to another drug, pyrovalerone, which is prescribed for weight loss overseas and sits on Schedule V, at the less-serious end of the DEA's scale. Van Linn said pyrovalerone and Alpha-PVP have similar chemical structures, but Trecki said pyrovalerone is seldom seen in the U.S. and was placed way down on Schedule V because of treaty obligations with countries that prescribe it. As for XLR-11 and other synthetic marijuana found in the case, Trecki equated them with THC, the active ingredient in marijuana, because they act on the same receptors in the brain to cause a euphoric effect. Rats also couldn't tell the difference in tests, he said. Trecki said the synthetic XLR-11 may be more potent than THC, meaning less is needed to get the same effect. Gram-per-gram, THC actually sits higher on the punishment scale than marijuana, so a gram of pure THC would be the equivalent of 167 grams of marijuana when deciding a prison sentence. Defense attorneys argued against the 1 to 167 ratio, noting it equated pure synthetics with pure THC. Substances seized during the investigation weren't pure. They were on inert plant material, and DEA chemists weren't able to test for purity. Lane noted the THC content in marijuana varies when comparing high-potency hybrids from Colorado to "Iowa ditch weed," and he asked the court to calculate synthetics on a 1 to 1 ratio with marijuana for sentencing purposes. Chief Judge Linda Reade will issue a ruling on the arguments at a later time and schedule dates to continue the sentencing hearings. - --- MAP posted-by: Matt