Pubdate: Sat, 25 Apr 2015 Source: Honolulu Star-Advertiser (HI) Copyright: 2015 Star Advertiser Contact: http://www.staradvertiser.com/info/Star-Advertiser_Letter_to_the_Editor.html Website: http://www.staradvertiser.com/ Details: http://www.mapinc.org/media/5154 Author: Alan Schwarz, New York Times OFFICIALS FEAR ILLICIT DRUG IS MORE POTENT, POPULAR A sharp rise in visits to emergency rooms and calls to poison control centers nationwide has health officials fearing that more potent and dangerous variations of a popular drug known as spice have reached the nation's streets. In the first three weeks of April, state poison control centers received about 1,000 reports of adverse reactions to spice - the street name for a family of synthetic substances that mimic the effects of marijuana - more than doubling the total from January through March, according to the American Association of Poison Control Centers. The cases, which can involve spice alone or in combination with other substances, have appeared four times as often this year as in 2014, the organization said. Health departments in Alabama, Mississippi and New York have issued alerts this month about more spice users being rushed to hospitals experiencing extreme anxiety, violent behavior and delusions, with some cases resulting in death. Similar increases have occurred in Arizona, Florida, New Jersey and Texas. The total number of fatalities nationwide this year is not available, health officials said. "We had one hospital in the Baton Rouge area that saw over 110 cases in February. That's a huge spike," said Dr. Mark Ryan, director of the Louisiana Poison Center. "When one of these new ingredients - something that's more potent and gives a bigger high - is released and gets into distribution, it can cause these more extreme effects." Experts were unsure whether the increase this month in spice-related emergencies reflected greater use of the drug or a particularly dangerous formulation. Ryan said a large portion of cases appeared to involve a form called mab-chminaca. State and federal law enforcement agencies have struggled to control the flow of synthetic cannabinoids, marijuana-looking substances that are sprayed with a hallucinogenic chemical and then smoked. Those chemicals, typically imported from China by U.S. distributors, come in hundreds of varieties; new formulations appear monthly, with molecules subtly tweaked to try to skirt the DEA's list of illegal drugs as well as drug-detecting urine tests. - --- MAP posted-by: Jay Bergstrom