Pubdate: Mon, 11 May 2015 Source: Western Star, The (CN NF) Copyright: 2015 The Western Star Contact: http://www.thewesternstar.com/ Details: http://www.mapinc.org/media/2523 Author: Liam Casey Page: 6 PARENTS OF EPILEPTIC GIRL WANT MARIJUANA OIL LEGAL Gwenevere Repetski turns three next month and she is finally able to crawl, a milestone her parents thought they would never see. She was just an infant when she was diagnosed with epilepsy, a debilitating neurological disorder that has left her developmentally delayed. "She was kind of like a bag of Jell-O," says her mother, Reagan Repetski. When she was two years old, she could hardly roll over when she was placed on her back, adds her father, Alex. Sitting in the living room of their Thornhill, Ont., home, the Repetskis recall their stressful and emotional journey in search of a treatment for Gwen. The first drug she was prescribed - Sabril - only managed to control her seizures for about a month. The next one was a steroid called ACTH, which her parents say caused her to gain half her body weight in three weeks. Disappointed at the lack of treatment options, Alex reduced his work hours and dove down the research rabbit hole. That's when he first read articles online about the success some people said they were having in reducing epileptic seizures with cannabidiol, one of several active cannabinoids found in the marijuana plant. Cannabidiol, or CBD, doesn't cause a high and, when mixed with an oil, has been widely touted as a potential therapy for hard-to-treat forms of epilepsy. But many doctors say there's little medical evidence yet to show if the compound is effective or even safe. Dr. Orrin Devinsky, a researcher at New York University's Langone Comprehensive Epilepsy Center, has done a safety study on the use of an extract of cannabidiol. Devinsky looked at the daily seizure logs of 137 patients, most of them children, who took a drug called Epidiolex- a purified form of CBD - for three months. The number of seizures decreased by an average of 54 per cent from the beginning of the study to the end, Devinsky reported last month at an American Academy of Neurology conference. "These results are of great interest, especially for the children and their parents who have been searching for an answer for these debilitating seizures," Devinsky said at the conference. However, he cautioned that there's no way to tell how much of the seizure reduction was due to the placebo effect in which the person's condition improves because they expect the drug to work. Similar research by Dr. Kevin Chapman of the University of Colorado recently raised similar questions. Chapman checked records of 58 young patients who used various types of CBD oils and found less than a third reported a significant seizure drop. - --- MAP posted-by: Jay Bergstrom