Pubdate: Thu, 25 Jun 2015 Source: Fayetteville Observer (NC) Copyright: 2015 Fayetteville Observer Contact: http://www.fayobserver.com Details: http://www.mapinc.org/media/150 Author: Paul Armentano MARIJUANA'S MEDICAL USES IGNORED The marijuana plant possesses an extensive history of human use dating back thousands of years, thus providing society with ample empirical evidence as to its relative safety and efficacy ("Our View: Medical marijuana should be allowed in North Carolina," June 1). Moreover, cannabis and its compounds are among some of the most well-studied biologically active substances of modern times. A search on PubMed, the repository for all peer-reviewed scientific papers, using the term "marijuana," yields more than 20,000 scientific papers referencing the plant and/or its constituents, nearly half of which have been published just within the past decade. Among this extensive body of literature are well over 100 randomized controlled studies, involving thousands of subjects, evaluating the safety and efficacy of cannabis or individual cannabinoids. (For the sake of comparison, a 2014 review of FDA-approved medications in the Journal of the American Medical Association reported, "The median number of pivotal trials per indication was two.") A review of several of these clinical trials assessing cannabis, published in The Open Neurology Journal, concludes, "Based on evidence currently available the Schedule I classification (for cannabis) is not tenable; it is not accurate that cannabis has no medical value, or that information on safety is lacking." You can read this review online here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358713/. State lawmakers are willfully ignoring modern science and overwhelming public opinion by refusing to consider legislation to allow qualified patients access to this safe and effective therapeutic agent. Paul Armentano, deputy director, National Organization for the Reform of Marijuana Laws Washington, D.C. - --- MAP posted-by: Jay Bergstrom