Source: Wall Street Journal Letters March 31 Contact: PainRelief Research Supports Marijuana Your editorialpage article (Marijuana is the Wrong Medicine," March 11) opposing medical use of marijuana is replete with mistnderstandings and erroneous information, reflecting either ignorance of the medical and scientific research or a cynical decision to ignore the facts. Foremost, the authors claim that marijuana actually eniances pain because it does not interact with the brain's "endorphin" system. Millions of Americans who have smoked it would probably disagree. But beyond the anecdotal evidence, there are decades of neuroscientific research into marijuana's painrelieving properties. Researchers have discovered an entire brain system for marijuana. Including receptors and neurotraosmitters. A few years ago they mapped the brain nuclei responsible for the drug's painrelieving effects. The authors are purportedly scientists: did they forget about this research? Have they not read a neuroscience Journal since 1985? This is wellfounded, governmentfunded research, which the authors distort or simply ignore. This offense against good science reporting is not excused by the expression of antidrug sentiments. PHILIP O. COFFIN Research Associate The Lindesrhith Center