Source: Orange County Register News Contact: 111097 Section: news,page 8 Author: Jim ABRAMS, A.P. MEASURE SIGNIFICANTLY CHANGING FDA IS OKD CONGRESS: Among the provisions is one speeding the approval of lifesaving drugs. WashingtonCulminating years of work,Congress on Sunday approved legislation that will bring basic changes to the Food and Drug Administration and accelerate the approval of lifesaving drugs. The bill, headed to President Clinton for his expected signature, gives Congress one major achievement as it brings a quarrelsome and highly partisan session to a close. The House passed the measure by voice vote just hours after Senate approval, which also came on a voice vote. The bill expands patient access to new drugs for lifethreatening illnesses, provides for accelerated approval of some drugs and medical devices, and allows the Health and Human Services secretary to accredit independent thirdparty groups to speed up reviews of lowrisk devices. It also reauthorizes a fiveyear program under which fees paid by drug companies have gone to hire 600 new reviewers, who have helped cut the backlog in new medicine approvals. Incentives are included for developing and testing medicines for children. The bipartisan agreement came after extensive negotiations on a number of issues: The final bill gives the FDA the right to request data for medicaldevice uses not listed on the devices' labels. As in the original bill, drug companies will be able to circulate reputable journal articles about offlabel use of drugs, but the FDA will also be able to review and approve those articles. Thirdparty review for medical devices was limited to apply mainly to lowerrisk devices. The final legislation preserves state authority to regulate cosmetics.