Pubdate: Wed, 08 Jul 1998 Source: South China Evening Post (Hong Kong) Contact: Website: http://www.scmp.com/ MARIJUANA SUBSTANCE MAY SAVE BRAIN CELLS AGENCE FRANCE-PRESSE In Washington A substance found in marijuana may help prevent brain cell death, say researchers. The team at the US Government's National Institutes of Health said they had found that cannabidiol, "a non-psychoactive, naturally occurring substance found in the marijuana plant, is a potent anti-oxidant which can prevent brain cell death". As an anti-oxidant, cannabibiol might hold promise for preventing brain damage in strokes, Alzheimer's disease, Parkinson's disease and even heart attacks, the researchers said in a report of their findings published on Monday in Proceedings of the National Academy of Sciences. The substance does not cause the "high" associated with marijuana smoking, said Aidan Hampson, the study's main author. "Cannabidiol is a desirable candidate for a side effect-free therapeutic agent," Mr Hampson said. "It does not produce euphoria." The substance protected cultured rat brain cells against damage, outperforming standard preventative medicines such as vitamins C and E, and the potent anti-oxidant BHT. Preliminary results from studies using cannabidiol in live animal models of stroke "are looking promising", Mr Hampson said. The substance passes readily from the blood into the brain and has been tested in humans over several weeks and at high doses, "with no apparent side effects reported". - --- Checked-by: Melodi Cornett