Source: Toronto Star (Canada) Contact: http://www.thestar.com/ Pubdate: Tues, 21 Sep 1998 Author: Thomas Walkom OTTAWA DRUG SCANDAL THREATENS ALL OF US A SCANDAL IS brewing in Ottawa, a scandal far more important than the question of how a sex-crazed U.S. president handled his videotaped grand jury testimony. The Ottawa scandal, unrolling in an obscure Sparks St. hearing room before a public service grievance tribunal, involves government stonewalling, allegations of cover-up and an all-too-cozy relationship between the powerful multinational drug industry and those federal officials who purport to regulate it. If the complainants at that hearing - six scientists employed by the federal Health Protection Branch - are correct, it is a scandal which puts the health of all Canadians at risk. The scientists claim that they were pressured to approve unsafe drugs. They claim the pressure came from their superiors who, in turn, were responding to demands from the big drug companies. In particular, they say they were pushed to give favourable reviews of controversial drugs used on animals. One was the genetically engineered growth hormone, recombinant bovine somatrotopin (rBST), which is used in the United States to increase milk production but which, mainly because of opposition from many dairy farmers, has not yet been approved for use in Canada. Another was the growth hormone Revalor-H, which is used to fatten cattle and which has been approved for Canadian use. It should be noted that many people eat beef. Others drink milk. The essence of the scientists' claims is that not enough attention is being paid to these basic facts of human diet. They argue that the government is pushing them to approve products which eventually may work their way into the food chain and injure humans. In the case of Revalor-H, researchers found the growth hormone altered some of the animals' internal organs. What they weren't able to find out was whether drug residues in these animals could also harm people. In the case of rBST, the researchers warned again that the long-term effects of the drug were simply unknown. They pointed out that certain side-effects of rBST - particularly the possibility that it might increase production of another hormone linked to cancer - argued for caution. All of this is troubling. Even more troubling is how the six scientists' worries have been handled. In one case, senior officials ordered an internal report on rBST rewritten to remove the critical parts. According to testimony at the public service tribunal, researchers in the branch's bureau of veterinary medicine were told they would be shipped off to where they would ``never be heard from again'' unless they approved controversial drugs. One researcher, Dr. Margaret Haydon, testified that senior managers warned she might be sued by Hoechst Canada Inc., the manufacturer of Revalor-H, if she didn't approve the drug. When that drug was finally approved, her boss wrote Hoechst promising to ``make up for the rough time (it) had with Revalor-H when we review (its) next submission.'' The grievance tribunal hearing itself, while technically public, is being conducted in a oddly minimalist manner. There are no transcripts of the evidence and reporters present say they can't hear all the questions and answers. The six scientists themselves have been ordered not to speak to the press. Even a Senate committee looking into the issue has been stonewalled. In June, health officials refused to give the committee an uncensored copy of the internal report criticizing the branch's handling of rBST. Senators were able to get at some of the disturbing evidence only after one of their researchers filed an access-to-information request. Throughout, the government's attempts to deal with the health branch controversy have only raised more questions. It has ordered two allegedly independent reviews of rBST. But one review is being done by an organization, the Canadian Veterinary Medical Association, already on record as favouring the legalization of rBST. The other is being carried out by the Royal College of Physicians and Surgeons. As The Star's Laura Eggertson revealed yesterday, one of the members of that committee - nutritionist RE9jeanne Gougeon - is a former consultant for Monsanto Canada, the manufacturer of rBST. She, too, is on record calling for the legalization of the growth hormone. Already, Health Canada is under investigation by the RCMP fraud squad for its approval - over the objections of its own scientists - of the Meme breast implant in the 1980s. This latest controversy, which has been curiously downplayed in the media, raises equally disturbing questions. With its starry-eyed attitude toward biotechnology, its naive trust of private industry and its helter-skelter approach to deregulation, the federal government is placing the health of the people at risk. That is the scandal. Thomas Walkom's column appears Tuesdays. - --- Checked-by: Don Beck