Pubdate: Sat, 17 Apr 1999 Source: Buffalo News (NY) Copyright: 1999 - The Buffalo News Fax: 716-856-5150 Website: http://www.buffnews.com/ Author: Patra A. Mangus, a professional herbalist for the past 27 years. She owns and operates Bi-Nutrients Herbal Information Center in Buffalo. CANNABIS HAS HERBAL BENEFITS RESEARCH CAN HELP UNLOCK As a child of the '60s, I was well aware of the recreational value of cannabis. (Yes, I inhaled, but as a non-smoker, I didn't do it very well.) Its virtues were extolled in music and films. The biggest joke was that you were using it for "medicinal purposes." Recently, there was an article in The News about an advisory panel that has concluded that compounds found in marijuana are effective for easing pain and relieving nausea. It turns out there are very real medicinal virtues to this forbidden herb. Cannabis has been used for centuries, by many cultures, as a drug to combat illness. It was officially listed in pharmaceutical repertoires in Europe and America. One of the first professionally prepared pharmaceuticals was a compound called Squire's Extract, used to treat typhus and rabies. There were dozens of cannabis-based remedies available by either prescription or over the counter, including Chlorodyne, a stomachic made by Squibb; Dr. Browns Sedative Tablets; One Day Cough Syrup; Syrup Tolou; Syrup Lobelia; and Corn Collodium. Parke-Davis manufactured several cannabis-based medications, including Casadein, Utroval and Veterinary Colic medicine. Some of the largest companies in the world were involved in their research and development. In time, the pharmaceutical companies stopped using cannabis because they were unable to standardize the levels of Tetrahydrocannabinol, Cannabidiol and Cannabinol. Without standardization, there was no profit in developing a drug from it. As anecdotal evidence stimulates interest in the therapeutic applications of cannabis, "empirical" data accumulates. From this data, scientific interest centers on conditions that responded well to the use of cannabis, the most familiar being nausea and vomiting caused by chemotherapy. As early as 1970, patients undergoing chemotherapy for Hodgkin's disease and other cancers discovered that if they smoked cannabis before receiving chemotherapy, they suffered less nausea and vomiting. Research has demonstrated that cannabis has very beneficial effects on patients suffering from glaucoma. It reduces the symptoms caused by high ocular-fluid levels. It is a proven appetite stimulant, which can be valuable to AIDS patients suffering from "wasting away syndrome." It even has the potential to be used in cases of anorexia. Cannabis is a herb that needs to be heated to release the effects of the synergistic compounds and help the body assimilate it. That is why smoking pot or baking it into food is the preferred way to consume it. It is also effective when made into a hot tea and sipped slowly. This form also helps flush the body of toxins and keeps the body hydrated. If the pharmaceutical companies can find a more efficient delivery mechanism, such as an inhaler, it appears that medical marijuana may become a reality. The active compound in Cannabis, called THC, has been produced in synthetic form by Ely Lilly and marketed under the generic name Dronabinol, and the trade name Marinol. It has been prescribed for many of the same things that cannabis has been used to treat. More research is being done to determine the mechanisms that allow cannabis to affect the body's neurological system. Hopefully, this is an area where science and medicine can join the long historical uses of plant medicine to benefit people with serious illness and speed their recovery. And, like the poppy plant, which gave us morphine, marijuana can become a standard part of our pharmacopoeia. PATRA A. MANGUS has been a professional herbalist for the past 27 years. She owns and operates Bi-Nutrients Herbal Information Center in Buffalo. For writer guidelines for columns appearing in this space, send a self- addressed, stamped envelope to Opinion Pages Guidelines, The Buffalo News, P.O. Box 100, Buffalo, N.Y. 14240. - --- MAP posted-by: Jo-D