Pubdate: 13 Dec 1999 Source: U.S. News and World Report (US) Copyright: 1999 U.S. News & World Report Contact: 1050 Thomas Jefferson Street, N.W., Washington, DC 20007-3871 Fax: (202) 955-2685 Feedback: http://www.usnews.com/usnews/usinfo/infomain.htm Website: http://www.usnews.com/ Forum: http://www.usnews.com/usnews/news/forum.htm Author: Chitra Ragavan and Jeff Glasser ECSTASY'S UPSURGE The Danger Of Being Young, Hip, And High On October 25, U.S. customs agents in Newark, N.J., were inspecting a 1992 BMW that had arrived from Germany on a freighter when they discovered the gas tank contained fuel of another sort: plastic bottles packed with nearly 25,000 doses of ecstasy, the hottest mind-altering drug on the club circuit today. When they went looking for the source, they ended up arresting four Russians in Columbus, Ohio. It's not an isolated case. The U.S. Customs Service has seized close to 3 million doses of ecstasy this year, a 700 percent increase from 1997. Ecstasy is not a street drug yet--it's a "club drug" with uncertain effects used by affluent teens and young professionals. Still, law enforcement officials are worried. "It's a drug that could hit America very quickly," says Steven Casteel, chief of intelligence for the Drug Enforcement Administration. The DEA banned ecstasy in 1985 but has been unable to stem the flow from the Netherlands. Tablets are distributed in the United States by Israeli and Russian crime syndicates through New York, Miami, and Los Angeles. Last week, the National Institute on Drug Abuse announced a $16 million increase in its "club drug" research and education budget. NIDA's director, Alan Leshner, says he wants to teach youth that "club drugs are not fun drugs." Benign Beginning. But many young Americans believe otherwise. One night recently, Stewart, a 24-year-old Washington, D.C., resident, popped a tablet stamped with a "Rolls-Royce" insignia (esctasy manufacturers use signature logos to promote brand loyalty) and sat down for what he called a "smooth, luxurious ride." Meanwhile his buddy Dave swallowed a potent "Ferrari." Soon, all their senses were heightened. "We were drinking Gatorade, and it was the best Gatorade we ever had," says Stewart. Merck, the German pharmaceutical company, created ecstasy in 1912, as a potential appetite suppressant. Some therapists also used it for marriage counseling–the "hug drug" creates a feeling of trust and empathy. But its popularity stems from the tremendous endurance it generates. It has found its niche with the advent of "raves," all-night techno-dance marathons, which hit Europe in the 1980s and the United States in the 1990s. The effects of the drug haven't been thoroughly studied. Ecstasy-related emergency-room admissions, while relatively few, skyrocketed from 68 in 1993 to 637 in 1997. The drug often seems so benign that users "don't get any warning signal," says Dr. George Ricaurte, a Johns Hopkins neurologist. Ricaurte says his research shows long-term ecstasy use could cause memory loss, sleeplessness, anxiety, and depression. And British researchers have linked ecstasy use during pregnancy to a higher rate of birth defects. But these studies are controversial because of the small numbers of human subjects. "Overall, the toxicity of this drug appears to be quite low in most humans," says Dr. John Morgan, a City University of New York pharmacologist. Law enforcement officials say the real danger is that ecstasy is becoming a "gateway" drug, leading to harder drugs. Miami police detective Eladio Paiz says users often take heroin, Valium, and other "downers" to lose their ecstasy high. Since 1997, 19 people are believed to have died in Florida after combining party drugs with alcohol or hard drugs. Says Jim McDonough, Florida's drug czar, "It's the drug soups that are killing them." - --- MAP posted-by: Richard Lake