Pubdate: Thu, 18 Mar 1999 Source: Associated Press Copyright: 1999 Associated Press Source: Standard-Times (MA) Copyright: 1999 The Standard-Times Contact: http://www.s-t.com/ Author: Randolph E. Schmid, Associated Press writer SCIENTIFIC REPORT BACKS MEDICAL MARIJUANA WASHINGTON - Marijuana has medical benefits for people suffering from cancer and AIDS and should undergo scientific trials to see how it works best, a panel of medical experts concluded yesterday in a report to the federal government. The drug remains illegal under federal law, despite ballot measures approving its use in Alaska, Arizona, California, Nevada, Oregon and Washington. The new report is sharpening debate over its use. The Institute of Medicine, an affiliate of the National Academy of Sciences, said marijuana's active ingredients can ease pain, nausea and vomiting. It urged the development of a standard way to use the drug, such as an inhaler. The conclusion was greeted warmly by most marijuana advocates, but opponents said they worry the report will encourage marijuana use. "Let us waste no more time in providing this medication through legal, medical channels to all the patients whose lives may be saved," said Daniel Zingale of AIDS Action. But Rep. Bill McCollum, R-Fla., who led the fight to get the House to condemn medical marijuana last fall, said he is "deeply concerned" the report might encourage people to smoke marijuana. It's known that some of the chemicals in marijuana can be useful, he acknowledged, but their place is in inhalers or pill form. "We should not sanction smoked marijuana because there is no way to control that," McCollum said. "Providing good medicine -- not marijuana -- is the compassionate response to patients' pain and illnesses," said Robert Maginnis of the conservative Family Research Council. He insisted doctors have other medicines to treat any ailment that marijuana can help. White House drug adviser Barry McCaffrey said the findings are unlikely to send pharmaceutical companies scrambling to do research on marijuana. "Our experience is there is little market interest," McCaffrey said. Ironically, the new analysis was requested and paid for by McCaffrey's White House Office of National Drug Control Policy, after an expert panel formed by the National Institutes of Health concluded in 1997 that some patients could be helped by marijuana, mainly cancer and AIDS victims. At the White House, spokesman Joe Lockhart said: "What we found out is that there may be some chemical compounds in marijuana that are useful in pain relief or anti-nausea, but that smoking marijuana is a crude delivery system. So I think what this calls for ... is further research." That's already under way at the NIH, which is running three studies of smoked marijuana and expects to approve a fourth this year. One study looks at marijuana's safety in people with AIDS, a second is checking the extent of medical marijuana use by patients of health maintenance organizations and the third is studying marijuana's ability to reduce nausea. Nearing approval is a study of marijuana's effect on pain. The National Cancer Institute is looking into the comparative value of a pill form of marijuana vs. a hormone in reducing nausea. Breaking ranks with the pro-medical marijuana groups was the National Organization for Reform of Marijuana Laws, which condemned the report as "tepid." "Clearly, the time has come for this administration to amend federal law to allow seriously ill patients immediate legal access," said Allen St. Pierre, executive director of the NORML Foundation. The arguments over using marijuana as a medication have grown particularly intense in the last few years in western states where supporters got initiatives on the ballot to legalize the practice. Voters in Alaska, Arizona, California, Nevada, Oregon and Washington have approved measures in support of medical marijuana. But the drug remains banned by federal law and doctors may be wary of prescribing it, even in those states. In its report, the Institute of Medicine said that because the chemicals in marijuana ease anxiety, stimulate the appetite, ease pain and reduce nausea and vomiting, they can be helpful for people undergoing chemotherapy and people with AIDS. It also said there is no evidence that use of marijuana leads to other drug use. But the panel warned that smoking marijuana can cause respiratory disease and called for the development of standardized forms of the drugs, called cannabinoids, that can be taken, for example, by inhaler. Even so, the panel said, there may be cases where patients could in the meantime get relief by smoking marijuana.