Pubdate: Fri, 19 Mar 1999 Source: International Herald-Tribune (Paris) Copyright: International Herald Tribune 1999 Contact: http://www.iht.com/ Author: David Brown, Washington Post Service PANEL SPLITS VERDICT ON MEDICAL MARIJUANA WASHINGTON - The active substances in marijuana may be moderately useful for treating such problems as pain, nausea and appetite loss, but smoked marijuana has little future as a medicine, according to a panel of experts advising the federal government. The long-awaited review, coming after several states legalized marijuana for medical use, was immediately seized upon by advocates of marijuana as an endorsement of their position. ''We are very pleased with this report, which clearly shows there is scientific evidence that marijuana has bona fide therapeutic effects for some patients,'' said Chuck Thomas, director of the Marijuana Policy Project. ''Patients already using marijuana should be given the benefit of the doubt, and should not be arrested.'' The report, prepared by 11 scientists convened by the National Academy of Sciences' Institute of Medicine, specifically warned against smoked marijuana because of the risk of lung damage. Therapeutic marijuana smoking should be permitted only in a few short clinical trials designed to assess claims for marijuana's usefulness as a pharmaceutical, it said. Barry McCaffrey, the White House official responsible for drug policy, who requested the report, said he endorsed it ''thoroughly,'' and called it a ''significant contribution to discussing the issue from a scientific and medical viewpoint.'' He said he would not oppose limited studies of smoked marijuana until a less-harmful way of inhaling the substance's active ingredients was found. ''I would note, however, that the report says smoked marijuana has little future as an approved medication,'' Mr. McCaffrey said. The panel reviewed published medical studies on marijuana's physiological effects and possible clinical benefits, and took testimony from researchers and patients. The claims for marijuana are very broad. People have used it as treatment for nausea caused by chemotherapy, appetite loss arising from AIDS, the painful spasms of multiple sclerosis, the pain of migraine headache, the sight-threatening condition glaucoma, and the memory loss of Alzheimer's disease. Reliable data on the drug's benefits, however, have been hard to get. The Drug Enforcement Administration places marijuana - along with heroin and several other addictive drugs - in the category of substances with ''a high abuse potential.'' This has made research on patients unusually difficult. - --- MAP posted-by: Richard Lake