Pubdate: Tue, 02 Aug 1999 Source: Tacoma News Tribune (WA) Copyright: 1999nTacoma News Inc. Contact: PO Box 11000, Tacoma, Wa. 98411 Fax: (206) 597-8451 Website: http://www.tribnet.com/ RITALIN DOESN'T LEAD TO LATER DRUG USE, NEW DATA SUGGEST Study Measured Effect On Hyperactive Boys CHICAGO - Hyperactive boys who were treated with stimulants such as Ritalin were one-third as likely to abuse alcohol and other drugs as teenagers than similar boys who had not been treated, a new study has found. Some experts not involved in the study said it was flawed and too small to reach meaningful conclusions. But authors of the study - which involved 212 boys, including 75 with attention-deficit hyperactivity disorder - said the findings should help allay concerns that giving children potentially addictive drugs such as Ritalin may promote harmful habits later. An estimated 3 million school-age children have this disorder, and as many as half may be taking Ritalin or other stimulants, past research indicates. "There has been a mythology that the use of these medications could 'prime' children to become addicts in the future or could develop 'a culture of drug taking,' " said Dr. Joseph Biederman of Massachusetts General Hospital, lead author of the study. It is published in the August issue of Pediatrics' "electronic pages," an Internet extension of the journal published by the American Academy of Pediatrics. "We believe that children with ADHD who are medically treated will have fewer problems resulting from their disorder and more successful lives, probably giving them fewer reasons to experiment with substance abuse," he added. Ritalin acts on dopamine, a brain chemical that helps regulate thinking. Ritalin is believed to calm hyperactivity by helping children's brains disregard distracting stimuli, such as classroom noise, so they can focus on learning. The subjects for the research were part of a previous study of families with an ADHD child and families with no ADHD children. The children and their mothers were interviewed on three occasions - when they entered the study, one year later and four years after enrollment. The authors studied 56 ADHD patients who were on medication, 19 ADHD patients not on medication and 137 without the disorder. At the study's end, 75 percent of the unmedicated ADHD subjects had substance abuse disorders, compared with 25 percent of the medicated subjects. Abused substances included alcohol, marijuana, hallucinogens, cocaine and other stimulants. Eighteen percent of the non-ADHD subjects were substance abusers. - --- MAP posted-by: Derek Rea