The United States is the midst of an opioid crisis. Ninety Americans die each day from opioid overdoses on prescription opioids, heroin, or fentanyl, and Massachusetts has not been spared. Many states are using the best available tools to battle the crisis, with an eye on developing better science and policy to put an end to the crisis. As more states implement either medical or legalized recreational cannabis policies, they should consider whether cannabis can play a role in the opioid crisis. [continues 601 words]