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Pubdate: Tue, 14 Jun 2005 Source: Roanoke Times (VA) Copyright: 2005 Roanoke Times Contact: http://www.roanoke.com/ Details: http://www.mapinc.org/media/368 Author: Laurence Hammack and Jen McCaffery Bookmark: http://www.mapinc.org/oxycontin.htm (Oxycontin/Oxycodone) OXYCONTIN'S MAKER UNDER INVESTIGATION IN SOUTHWEST VIRGINIA A Purdue Pharma Spokesman Confirmed The Investigation, Saying "We Are Aware Of Nothing That Should Reasonably Lead To Charges." Federal authorities in Southwest Virginia are investigating the drug company Purdue Pharma for its marketing of the painkiller OxyContin, a company spokesman confirmed Monday. "Purdue has total confidence in the honesty and integrity of its officers and directors, and is cooperating in that investigation," said Purdue Pharma spokesman Tim Bannon. "We are aware of nothing that should reasonably lead to charges as a result of this investigation." Bannon said the company first learned of the investigation in December 2002. This is not the first time Purdue Pharma has faced questions from Virginia prosecutors. In 2001, then-Attorney General Mark Earley requested a meeting with company officials to discuss reports of growing abuse of the painkiller, which at the time was described as the drug of choice for abusers in far Southwest Virginia. "There have been a number of inquiries, but none of them have been criminal in nature," Bannon said. "We have responded to all of those inquiries." Heidi Coy, spokeswoman for the U.S. Attorney's Office in Roanoke, declined to comment Monday, citing the office's policy of neither confirming nor denying an ongoing investigation. An attorney in New York City, Paul Hanly, said one of his clients was subpoenaed to testify before a federal grand jury in Abingdon in early 2004. He described his client as a legal assistant who worked in the head office of Purdue Pharma in Stamford, Conn. He declined to identify his client. Federal prosecutor Randy Ramseyer interviewed Hanly's client about when company officials became aware of the abuse of OxyContin, Hanly said. Ramseyer did not ultimately call Hanly's client to testify before the grand jury, Hanly said. He does not know why. Ramseyer, who is based in Abingdon, could not be reached for comment Monday. Hanly said his understanding was that the investigation concerns when Purdue Pharma officials found out about the widespread abuse of OxyContin. Purdue Pharma has maintained that company officials only knew about isolated cases of abuse until the winter of 2000, when they were alerted to problems by the U.S. Attorney in Maine, Hanly said. But Hanly said internal documents his client knew about showed that company officials knew that people were crushing, snorting and injecting OxyContin dating back to 1997 and 1998. They also knew that the abuse was widespread, Hanly said. He also represents several hundred clients around the United States who have sued Purdue Pharma after they became addicted to OxyContin. Company officials continued to sell billions of dollars worth of OxyContin even though they knew early on it was being abused, according to Hanly. The company's marketing practices have long been a concern of critics. However, a probe by the Government Accountability Office, the investigative arm of Congress, stopped short of linking Purdue Pharma's promotional efforts to widespread abuse of OxyContin. A GAO report released last year noted that some company sales representatives received large bonuses for targeting selected doctors. The amount of bonuses the company rewarded to its sales force grew from $1 million in 1996, the year OxyContin hit the market, to $40 million in 2001, according to the report. Purdue Pharma changed part of its policy regarding bonuses four years ago following a meeting with federal authorities in Roanoke, the report stated. OxyContin abuse first became a key priority among Virginia law enforcement officials in 2001, when figures from the medical examiner's office in Roanoke showed a rapidly increasing number of fatal overdoses from oxycodone. Since then, deaths from methadone and other prescription drugs have surpassed those caused by oxycodone, the key ingredient in OxyContin. Last year, 37 people died from oxycodone overdoses in the western half of Virginia, according to Dr. William Massello, assistant chief medical examiner. Methadone caused 69 deaths in the region last year, Massello said, and another 59 were attributed to hydrocodone, a class of painkillers that includes Vicodin and Lortab. Deaths from oxycodone ranked third in the region, which saw 201 total drug deaths last year - a decrease of about 20 from the year before. Although questions about Purdue Pharma's marketing of OxyContin have been raised by critics of the company, lawsuits filed by people who claimed they became addicted to the drug while taking it as patients have mostly been unsuccessful. Last year, a federal judge in Abingdon dismissed lawsuits filed by three men who claimed the company over-promoted the painkiller while ignoring its risks - rendering them addicts while reaping billions in sales. In dismissing the cases, U.S. District Court Judge James Jones said the lawsuits were not the proper forum to address several questions, one of them: "Did Purdue oversell OxyContin, for its own profit?" - --- MAP posted-by: Larry Seguin