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Pubdate: Fri, 30 Apr 2004 Source: Morning Star, The (CN BC) Copyright: 2004 The Morning Star Contact: http://www.vernonmorningstar.com/ Details: http://www.mapinc.org/media/1352 IT'S FOR YOUR OWN PROTECTION Many people think that smoking marijuana has no long-term effects on them or their brains; it's a common myth. In fact, the long-term effects of cannabis are very similar to those of other drugs such as cocaine, heroin and alcohol in the changes that it produces within the brain. Studies have shown that long-term exposure to cannibinoids leads to changes in the brain that activate stress-like responses during withdrawal. These changes may ultimately lead to easier addiction of other substances as well; since the brain becomes more vulnerable to abuse and addiction and is more easily changed by drugs in the future. Another effect is in the Dopamine Neurons, which are directly or indirectly affected by all drugs of abuse, these neurons are responsible for the regulation of motivation and reward. Another myth about the seemingly harmless Marijuana plant is that it's not addictive, wrong again. Dr. Alan I. Leshner, director of the National Institute on Drug Abuse, National Institute of Health has done extensive research on this subject and found that a large number of chronic marijuana users become addicted and animals used in research have even showed distinct withdrawal symptoms when taken off the drug after extensive use. After repeated use of marijuana as with most other drugs of abuse a person begins to become tolerant to the drug. There are several reasons for this, the brain may become used to having a certain amount of the drug present and thus doesn't respond the same way it did initially. The body may become more effective at metabolizing and breaking down the drug; this reduces the amount of the drug in the bloodstream. Another possibility is that the cells of the body may cause changes to the activity of the receptors and therefore become more resistant to the drug. No matter what the reason, these changes, inducing tolerance, force the drug user to take increasingly higher dose over time, in order to get the same "high" that they're used to, this increased of the drug simply causes more and more long and short-term effects on their bodies and brains. Marijuana works because of THC (Tetrahydrocannabinol); a drug found in cannabis, as the smoke is inhaled it is quickly absorbed into the bloodstream through the lungs, which carries the chemical through the blood to the organs including the brain. THC causes a reaction with cannabinoid receptors, which are found in several places throughout the brain, these places are involved with the brains function of memory, concentration, perception and movement. When the interaction occurs it effects the normal functioning of these neurons. Studies are being done in Australia in which sophisticated brain imaging technology is being used to show how closely the changes produced by long-term marijuana use mirror those associate with schizophrenia. Test subjects are people aged between 17 and 24 who have smoked at like 20,000 "joints" in the past 2 years. The research showed that chronic cannabis users experienced impaired frontal brain functioning, which interfere with attention, memory and concentration and was similar to some symptoms of schizophrenia. Dr. Cohen commented that, "Cannabis affects the neutral networks, or the architecture, of the brain's refrontal cortex in a similar way to schizophrenia." Previous studies have also showed that heavy adolescent users are increasing their risk of developing schizophrenia by up to six times, so it seems marijuana use does have seem possibly quite serious effects. A report produced by the Seattle Transhumanists in June 2001 gives several facts about the cognitive effects of Cannabis. Not only does THC effect short-term memory it also interferes with memory formation in the future, therefore even after the consumption of the drug the brain is still being affected in growth patterns. Some of the motion effects on the Striatum of the brain are implicated in motion disorders Parkinson's and Huntington's disease, as well as increased Obsessive-Compulsive behavior, but reduction in Tics from Turret's Syndrome. THC also impairs reaction time in visual scanning in the long run after frequent use of the drug. It is estimated that about 70 million Americans have tried marijuana and of this number about 10-14 become dependent of the drug, yet some scientist still claim that there is no addictive chemical in the drug at all. A study involving monkey's gave the animals a lever in which injected them with THC each time they pulled it, once they figured it out the monkey's pulled the lever approximately 30 times per minute. Although this does not conclude that it is addictive because the monkey's may simply have enjoyed the high, it is still clear that there is a possibility something in the drug gets certain people (and animals) hooked. There are many commonly believed myths about marijuana, like it's impossible to get addicted to, there are no long-term effects, it doesn't effect your driving abilities, etc. The truth is studies have shown that the use of Cannabis and the effects it has on the body and mind are similar if not greater than those of alcohol and smoking as well as the brain related effects of hard drugs. So in case you didn't think about it before, it's illegal for a reason... you're protection. - --- MAP posted-by: Richard Lake